Target Name: CCDC126
NCBI ID: G90693
Other Name(s): Coiled-coil domain-containing protein 126 | MGC104248 | coiled-coil domain containing 126 | CC126_HUMAN | Coiled-coil domain containing 126 | Alpha-1,3(6)-mannosylglycoprotein beta-1,6-N-acetyl-glucosaminyltransferase-like | FLJ23031 | OTTHUMP00000202195 | OTTHUMP00000202196

CCDC126: A Potential Drug Target and Biomarker for Neurodegenerative Diseases

CDC126 is a protein that is expressed in various tissues of the brain and is involved in the development and progression of neurodegenerative diseases. Its function and structure have been extensively studied, and its potential as a drug target or biomarker in these diseases have been proposed. In this article, we will explore the biology of CDC126 and its potential as a drug target and biomarker.

Structure and Function

CDC126 is a protein that is composed of a unique domain structure that consists of a coiled-coil, a transmembrane region, and a cytoplasmic tail. The coiled-coil region is the protein's most prominent feature and is responsible for its unique structure and function.

The coiled-coil region of CDC126 is made up of a series of amino acids that form a repeating pattern of alpha helices. This pattern of helices iswhat gives the protein its unique structure and allows it to adopt a specific 3D shape. The coiled-coil region is also responsible for the protein's stability and for maintaining its integrity.

CDC126 is also involved in the regulation of various cellular processes, including cell adhesion, migration, and the transport of vesicles in the brain. These functions are critical for the development and progression of neurodegenerative diseases, and the dysfunction of CDC126 has been implicated in the development of a wide range of neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease, and Huntington's disease.

CDC126 has also been shown to play a role in the regulation of neurotransmitter release from neurons, which is critical for the function of the brain. The dysfunction of CDC126 has been implicated in the development of neurotransmitter-related neurodegenerative diseases, including depression and anxiety.

Potential as a Drug Target

CDC126 has been identified as a potential drug target for a wide range of neurodegenerative diseases due to its involvement in the development and progression of these diseases. The dysfunction of CDC126 has been shown to be involved in the pathophysiology of neurodegenerative diseases, and targeting this protein has the potential to provide new treatments for these diseases.

One approach to targeting CDC126 is to use small molecules that can modulate the activity of the protein. This approach has been used to identify compounds that can inhibit the function of CDC126 and prevent its accumulation in neurodegenerative diseases.

Another approach to targeting CDC126 is to use antibodies that can specifically bind to the protein and prevent it from interacting with its downstream targets. This approach has been used to identify antibodies that can specifically bind to CDC126 and protect against neurodegenerative diseases.

Potential as a Biomarker

CDC126 has also been identified as a potential biomarker for the diagnosis and monitoring of neurodegenerative diseases. The dysfunction of CDC126 has been shown to be involved in the development and progression of a wide range of neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease, and Huntington's disease.

Therefore, measuring the expression and function of CDC126 could be a useful biomarker for the diagnosis and monitoring of neurodegenerative diseases. This could help to improve the accuracy and sensitivity of neurodegenerative disease diagnosis and provide new insights into the underlying mechanisms of these diseases.

Conclusion

In conclusion, CDC126 is a protein that is involved in the development and progression of neurodegenerative diseases. Its unique structure and function, as well as its involvement in the regulation of various cellular processes, make it an attractive target for drug development. Additionally, its potential as a biomarker for neurodegenerative diseases makes it an important tool for the diagnosis and monitoring of these diseases. Further research is needed to fully understand the role of CDC126 in

Protein Name: Coiled-coil Domain Containing 126

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