Target Name: CCDC127
NCBI ID: G133957
Other Name(s): OTTHUMP00000220452 | coiled-coil domain containing 127 | FLJ25701 | CC127_HUMAN | Coiled-coil domain containing 127 | Coiled-coil domain-containing protein 127

CCDC127: A Potential Drug Target for PDGF-BB, TGF-?1 and NF-??B

CCDC127, also known as OTTHUMP00000220452, is a protein that is expressed in various tissues throughout the body. It is a member of the CCDC family, which is known for its role in cell signaling and communication.

One of the main functions of CCDC127 is to regulate the activity of various signaling pathways that are involved in cellular processes such as cell growth, differentiation, and inflammation. It does this by interacting with a variety of different proteins, including the protein known as PDGF-BB.

PDGF-BB is a protein that is involved in cell signaling and growth, and it is a key signaling molecule for many different types of cancer. It is produced by the cells themselves, but it can also be found in the surrounding tissue and can be administered to cells as a treatment.

CDC127 is thought to be a potential drug target for PDGF-BB because it is involved in the regulation of PDGF-BB's activity. This is important because PDGF-BB has been shown to play a role in the development and progression of many different types of cancer, including breast, lung, and ovarian cancer.

In addition to its role in regulating PDGF-BB activity, CCDC127 is also involved in the regulation of many other signaling pathways that are important for cellular growth and development. It does this by interacting with a variety of different proteins, including the protein known as TGF-β1.

TGF-β1 is a protein that is involved in cell signaling and growth, and it is a key signaling molecule for many different types of cancer. It is produced by the cells themselves, but it can also be found in the surrounding tissue and can be administered to cells as a treatment.

CDC127 is thought to be a potential drug target for TGF-β1 because it is involved in the regulation of TGF-β1's activity. This is important because TGF-β1 has been shown to play a role in the development and progression of many different types of cancer, including breast, lung, and ovarian cancer.

In addition to its role in regulating TGF-β1 activity, CCDC127 is also involved in the regulation of many other signaling pathways that are important for cellular growth and development. It does this by interacting with a variety of different proteins, including the protein known as NF-kappa-B.

NF-kappa-B is a protein that is involved in cell signaling and inflammation. It is produced by the cells themselves, but it can also be found in the surrounding tissue and can be administered to cells as a treatment.

CDC127 is thought to be a potential drug target for NF-kappa-B because it is involved in the regulation of NF-kappa-B's activity. This is important because NF-kappa-B has been shown to play a role in the development and progression of many different types of cancer, including breast, lung, and ovarian cancer.

In conclusion, CCDC127 is a protein that is involved in the regulation of various signaling pathways that are important for cellular growth and development. It is a potential drug target for PDGF-BB, TGF-β1, and NF-kappa-B, which are all known to play a role in the development and progression of many different types of cancer. Further research is needed to fully understand the role of CCDC127 in cancer development and to identify potential strategies for its targeting.

Protein Name: Coiled-coil Domain Containing 127

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