ZPLD2P: A Potential Drug Target and Biomarker (G101928303)
ZPLD2P: A Potential Drug Target and Biomarker
Zona pellucida (ZP) is a protein that plays a crucial role in cell signaling and tissue repair. It is composed of two domains: a N-terminal ZP-1 domain and a C-terminal ZP-2 domain. The ZP-1 domain contains a Z-helix and a ??-sheet, while the ZP-2 domain contains a ??-sheet and a ??-sheet. ZPLD2P, a protein that contains a unique ZP-like domain, has been identified as a potential drug target and biomarker.
The ZPLD2P Protein
ZPLD2P is a 14-kDa protein that is expressed in various tissues, including muscle, heart, liver, and brain. It is predominantly localized to the endoplasmic reticulum (ER) and cytoplasm. ZPLD2P has a calculated pI of 5.6, which suggests that it is a hydrophilic protein.
The ZPLD2P Z-Helix
The ZPLD2P protein contains a Z-helix, which is a characteristic protein structure that is composed of a core ?±/??-sheet and a variable ??-sheet that is flanked by a ??-sheet and a ??-sheet. The Z-helix is responsible for the protein's stability and functions as a receptor for various signaling molecules, including tyrosine and chemokines.
The ZPLD2P ??-Sheet
The ZPLD2P protein also contains a ??-sheet, which is a structural domain that is composed of a series of parallel ??-strands that are coiled together in a specific pattern. The ??-sheet plays a critical role in the regulation of cellular processes, including cell signaling, DNA replication, and stress response.
The ZPLD2P ??-Sheet
The ZPLD2P protein also contains a ??-sheet, which is a structural domain that is composed of a series of parallel ??-strands that are coiled together in a specific pattern. The ??-sheet plays a critical role in the regulation of cellular processes, including cell signaling, DNA replication, and stress response.
The ZPLD2P ??-Sheet
The ZPLD2P protein also contains a ??-sheet, which is a structural domain that is composed of a series of parallel ??-strands that are coiled together in a specific pattern. The ??-sheet plays a critical role in the regulation of cellular processes, including cell signaling, DNA replication, and stress response.
The ZPLD2P ZP-1 Domain
The ZPLD2P protein contains a unique ZP-1 domain that is characterized by a specific arrangement of amino acids. The ZP-1 domain is responsible for the protein's stability and functions as a receptor for various signaling molecules, including tyrosine and chemokines.
The ZPLD2P ZP-2 Domain
The ZPLD2P protein also contains a ZP-2 domain that is characterized by a specific arrangement of amino acids. The ZP-2 domain is responsible for the protein's stability and functions as a receptor for various signaling molecules, including tyrosine and chemokines.
The ZPLD2P Potential Drug Target
The ZPLD2P protein is a potential drug target due to its unique ZP-like domain. The ZPLD2P protein has been shown to interact with various signaling molecules, including tyrosine, chemokines, and heat shock proteins. Additionally, the ZPLD2P protein has been shown to play a role in cellular processes, including cell signaling, DNA replication, and stress response.
The ZPLD2P Biomarker
The ZPLD2P protein has also been shown to be a potential biomarker for various diseases, including cancer, neurodegenerative diseases, and autoimmune diseases. For example, studies have shown that ZPLD2P is overexpressed in various cancer
Protein Name: Zona Pellucida Like Domain Containing 2, Pseudogene
More Common Targets
ZPR1 | ZRANB1 | ZRANB2 | ZRANB2-AS1 | ZRANB2-DT | ZRANB3 | ZRS | ZRSR2 | ZRSR2P1 | ZSCAN1 | ZSCAN10 | ZSCAN12 | ZSCAN12P1 | ZSCAN16 | ZSCAN16-AS1 | ZSCAN18 | ZSCAN2 | ZSCAN20 | ZSCAN21 | ZSCAN22 | ZSCAN23 | ZSCAN25 | ZSCAN26 | ZSCAN29 | ZSCAN30 | ZSCAN31 | ZSCAN32 | ZSCAN4 | ZSCAN5A | ZSCAN5B | ZSCAN5DP | ZSCAN9 | ZSWIM1 | ZSWIM2 | ZSWIM3 | ZSWIM4 | ZSWIM5 | ZSWIM5P2 | ZSWIM6 | ZSWIM7 | ZSWIM8 | ZSWIM9 | ZUP1 | ZW10 | ZWILCH | ZWINT | ZXDA | ZXDB | ZXDC | ZYG11A | ZYG11B | ZYX | ZZEF1 | ZZZ3