NME6: A Potential Drug Target for DNA Replication and Gene Expression

Target Name: NME6

NCBI ID: G10201

NME6: A Potential Drug Target for DNA Replication and Gene Expression

Nucleoside diphosphate kinase 6 (NME6) is a protein that plays a crucial role in cellular processes such as DNA replication, transcription, and repair. It is a key enzyme in the DNA replication machinery, which is responsible for copying the genetic material from the parent cell to the daughter cell during the cell cycle.

NME6 is a protein that is expressed in all cell types and is highly conserved across different species. It is a nuclear protein and is localized to the nucleoplasm. NME6 is composed of two distinct isoforms, isoform 1 and isoform 2.

Isoform 1 is the most abundant isoform, and it is responsible for the majority of NME6-mediated cellular processes. Isoform 2 is a less abundant isoform, but it is still involved in NME6-mediated cellular processes.

NME6 is involved in the replication of DNA in the nucleus. It is essential for the initiation of DNA replication, as it provides the energy and structural components for the initiation of the replication process.

During DNA replication, NME6 is involved in the formation of the double helix. It is one of the key enzymes that enables the formation of the double helix, which is the standard form of DNA.

In addition to its role in DNA replication, NME6 is also involved in the regulation of gene expression. It is a negative regulator of gene expression, which means that when NME6 is activated, it can prevent the expression of certain genes.

NME6 is a protein that has been identified as a potential drug target. Its involvement in DNA replication and gene expression make it an attractive target for small molecules that can modulate its activity.

One of the potential benefits of targeting NME6 is that it can be used to treat a variety of diseases. Its involvement in DNA replication and gene expression makes it an attractive target for drugs that can inhibit its activity. This can lead to the inhibition of tumor growth and the development of cancer.

Another potential benefit of targeting NME6 is that it can be used to treat a variety of genetic disorders. Its involvement in DNA replication and gene expression makes it an attractive target for drugs that can modulate its activity and improve the survival of individuals with genetic disorders.

Overall, NME6 is a protein that is involved in a variety of cellular processes. Its involvement in DNA replication and gene expression make it an attractive target for small molecules that can modulate its activity. As research continues to advance, it is likely that new treatments will be developed that can target NME6 and improve the health and well-being of individuals.

Protein Name: NME/NM23 Nucleoside Diphosphate Kinase 6

Functions: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Inhibitor of p53-induced apoptosis

More Common Targets