NOP10: A Transmembrane Protein Involved in Cellular Processes and Disease

Target Name: NOP10

NCBI ID: G55505

NOP10: A Transmembrane Protein Involved in Cellular Processes and Disease

Nucleolar protein 10 (NOP10) is a protein that is expressed in a variety of cell types, including neurons, muscle cells, and red blood cells. It is a member of the nucleolar protein (NOP) family, which is a group of proteins that are involved in the maintenance and organization of the nuclear genome.

NOP10 is unique among the NOP proteins in that it is a transmembrane protein. This means that it spans the cell membrane and is involved in various processes that are specific to the cell membrane environment. NOP10 is also unique in that it has a unique signal transduction mechanism.

The NOP10 protein is involved in the regulation of various cellular processes that are important for cell growth, including cell division, cytoskeletal organization, and chromatin structure. It is also involved in the regulation of cell survival and in the development and progression of various diseases, including cancer.

Due to its unique role in cell biology, NOP10 has been identified as a potential drug target. Researchers are currently studying the potential mechanisms of NOP10 and are exploring ways to use it as a therapeutic agent.

One of the main research efforts is focused on understanding the function of NOP10 in cancer. Studies have shown that NOP10 is often overexpressed in various types of cancer, and that it is involved in the regulation of cell proliferation and survival.

In addition to its role in cancer, NOP10 is also involved in the regulation of normal cellular processes, including cell growth, differentiation, and survival. This makes it an attractive target for researchers who are studying the mechanisms of normal cell biology.

Another area of research is the study of the potential uses of NOP10 as a drug. Studies have shown that NOP10 can be used to inhibit the growth of cancer cells in a variety of models, including cell culture and animal models. In addition, NOP10 has been shown to have anti-inflammatory effects and to have a positive impact on the immune system.

Overall, NOP10 is a unique and promising protein that has the potential to be a drug target or biomarker. Further research is needed to fully understand its role in cell biology and its potential as a therapeutic agent.

Protein Name: NOP10 Ribonucleoprotein

Functions: Required for ribosome biogenesis and telomere maintenance. Part of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Each rRNA can contain up to 100 pseudouridine ('psi') residues, which may serve to stabilize the conformation of rRNAs. May also be required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse transcriptase (TERT) holoenzyme

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