Nucleophosmin 1 as A Cancer and Neurodegenerative Disease Research Target

Nucleophosmin 1 as A Cancer and Neurodegenerative Disease Research Target

Nucleophosmin 1 (NPM1P13) is a protein that is found in the nucleolus, which is the key structure in the nucleus of a cell. NPM1P13 plays a vital role in the proper functioning of the cell, and its levels have been linked to a number of diseases, including cancer.

One of the reasons that NPM1P13 has been identified as a potential drug target is its role in the development and progression of cancer. NPM1P13 has been shown to be highly expressed in a variety of cancer types, including breast, ovarian, and prostate cancer. Additionally, studies have shown that inhibiting NPM1P13 can lead to a reduction in cancer cell proliferation and the formation of new blood vessels, which can be a promising approach to cancer treatment.

Another potential mechanism by which NPM1P13 may be targeted as a drug is its role in the regulation of cell death. NPM1P13 has been shown to play a role in the production of the protein Apoptosis-associated protein-1 (AP-1), which is involved in cell death. Additionally, studies have shown that inhibiting NPM1P13 can lead to increased levels of AP-1 and an increase in cell death, which may be a potential mechanism of action for a drug that targets NPM1P13.

In addition to its potential role as a drug target, NPM1P13 has also been identified as a potential biomarker for a number of diseases. For example, studies have shown that increased levels of NPM1P13 have been associated with the development of a variety of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. Additionally, NPM1P13 has been shown to be highly expressed in a variety of tissues and fluids, which may make it a useful diagnostic marker for a number of conditions.

Overall, NPM1P13 is a protein that has the potential to be a drug target or biomarker for a variety of diseases. Further research is needed to fully understand its role in the functioning of the cell and its potential as a therapeutic target.

Protein Name: Nucleophosmin 1 Pseudogene 13

More Common Targets

NPM1P21 | NPM1P22 | NPM1P25 | NPM1P27 | NPM1P28 | NPM1P35 | NPM1P42 | NPM1P47 | NPM1P48 | NPM2 | NPM3 | NPNT | NPPA | NPPA-AS1 | NPPB | NPPC | NPR1 | NPR2 | NPR3 | NPRL2 | NPRL3 | NPS | NPSR1 | NPSR1-AS1 | NPTN | NPTN-IT1 | NPTX1 | NPTX2 | NPTXR | NPVF | NPW | NPY | NPY1R | NPY2R | NPY4R | NPY4R2 | NPY5R | NPY6R | NQO1 | NQO2 | NR0B1 | NR0B2 | NR1D1 | NR1D2 | NR1H2 | NR1H3 | NR1H4 | NR1I2 | NR1I3 | NR2C1 | NR2C2 | NR2C2AP | NR2E1 | NR2E3 | NR2F1 | NR2F1-AS1 | NR2F2 | NR2F2-AS1 | NR2F6 | NR3C1 | NR3C2 | NR4A1 | NR4A2 | NR4A3 | NR5A1 | NR5A2 | NR6A1 | NRAD1 | NRADDP | NRAP | NRARP | NRAS | NRAV | NRBF2 | NRBF2P4 | NRBP1 | NRBP2 | NRCAM | NRDC | NRDE2 | NREP | NRF1 | NRG1 | NRG2 | NRG3 | NRG4 | NRGN | NRIP1 | NRIP2 | NRIP3 | NRIP3-DT | NRIR | NRK | NRL | NRM | NRN1 | NRN1L | NRON | NRP1 | NRP2