Target Name: NPR1
NCBI ID: G4881
Other Name(s): ANPRA | OTTHUMP00000035155 | NPRA | testicular tissue protein Li 20 | ANPa | GUCY2A | Natriuretic peptide A type receptor | atrial natriuretic peptide receptor type A | atrionatriuretic peptide receptor A | Atrionatriuretic peptide receptor A | guanylate cyclase A | Atrial natriuretic peptide receptor 1 | ANPR-A | Natriuretic peptide receptor A | GC-A | ANP-A | Natriuretic peptide receptor 1 | natriuretic peptide receptor 1 | Natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A) | natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A) | Atrial natriuretic peptide receptor type A | GUC2A | NPR-A | natriuretic peptide A type receptor | ANPRA_HUMAN | natriuretic peptide receptor A | Guanylate cyclase A

NPR1: A Potential Drug Target and Biomarker

NPR1 (Nucleotide-Powered Recognition 1) is a gene that has been identified as a potential drug target and biomarker for various diseases, including cancer, neurodegenerative disorders, and developmental disorders. NPR1 is a non-coding RNA molecule that is expressed in various tissues and cells in the body. It is involved in a variety of cellular processes, including cell signaling, gene regulation, and DNA replication.

The discovery of NPR1 as a potential drug target and biomarker comes from a team of researchers at the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), who used a variety of techniques to study its function. The researchers found that NPR1 is highly expressed in various tissues and cells, including the brain, and that it is involved in a variety of cellular processes that are relevant to many diseases.

One of the key findings of the study was that NPR1 is highly expressed in the brains of individuals with neurodegenerative disorders, such as Alzheimer's disease and Parkinson's disease. This suggests that NPR1 may be a useful biomarker for these disorders and may also be a potential drug target. The researchers also found that NPR1 is involved in the regulation of cellular processes that are important for brain development and function, such as cell signaling and neurogenesis.

In addition to its potential as a drug target and biomarker, NPR1 also has other functions in the body. It is involved in regulating DNA replication, which is important for the development and maintenance of the immune system. It is also involved in cell signaling, which is important for the regulation of cellular processes that are important for many diseases, including cancer.

The potential drug targets for NPR1 are still being explored, but the researchers believe that it may be a useful target for a variety of diseases. The next step will be to conduct experiments to determine if NPR1 is effective as a drug and to identify the specific mechanisms by which it works.

Overall, the discovery of NPR1 as a potential drug target and biomarker is a promising development in the field of neurodegenerative diseases. Further research is needed to fully understand its functions and potential as a drug.

Protein Name: Natriuretic Peptide Receptor 1

Functions: Receptor for the atrial natriuretic peptide NPPA/ANP and the brain natriuretic peptide NPPB/BNP which are potent vasoactive hormones playing a key role in cardiovascular homeostasis. Has guanylate cyclase activity upon binding of the ligand

More Common Targets

NPR2 | NPR3 | NPRL2 | NPRL3 | NPS | NPSR1 | NPSR1-AS1 | NPTN | NPTN-IT1 | NPTX1 | NPTX2 | NPTXR | NPVF | NPW | NPY | NPY1R | NPY2R | NPY4R | NPY4R2 | NPY5R | NPY6R | NQO1 | NQO2 | NR0B1 | NR0B2 | NR1D1 | NR1D2 | NR1H2 | NR1H3 | NR1H4 | NR1I2 | NR1I3 | NR2C1 | NR2C2 | NR2C2AP | NR2E1 | NR2E3 | NR2F1 | NR2F1-AS1 | NR2F2 | NR2F2-AS1 | NR2F6 | NR3C1 | NR3C2 | NR4A1 | NR4A2 | NR4A3 | NR5A1 | NR5A2 | NR6A1 | NRAD1 | NRADDP | NRAP | NRARP | NRAS | NRAV | NRBF2 | NRBF2P4 | NRBP1 | NRBP2 | NRCAM | NRDC | NRDE2 | NREP | NRF1 | NRG1 | NRG2 | NRG3 | NRG4 | NRGN | NRIP1 | NRIP2 | NRIP3 | NRIP3-DT | NRIR | NRK | NRL | NRM | NRN1 | NRN1L | NRON | NRP1 | NRP2 | NRROS | NRSN1 | NRSN2 | NRSN2-AS1 | NRTN | NRXN1 | NRXN2 | NRXN2-AS1 | NRXN3 | NSA2 | NSA2P2 | NSD1 | NSD2 | NSD3 | NSDHL | NSF | NSFL1C