Nucleolar Protein 12: Potential Drug Target (G79159)

Target Name: NOL12

NCBI ID: G79159

Nucleolar Protein 12: Potential Drug Target

Nucleolar protein 12 (NOL12) is a protein that is expressed in various cell types, including muscle, nerve, and heart cells. It is a member of the nucleolar protein family, which is a group of proteins that are involved in the maintenance and repair of the nuclear genome. NOL12 is unique among these proteins because it is expressed in the nucleolus, which is the organ responsible for the production of RNA.

The function of NOL12 is not well understood, but it is thought to play a role in the regulation of gene expression. This is suggested by the fact that NOL12 is highly expressed in RNA-producing cells, such as muscle and nerve cells, and that it is able to interact with other proteins involved in gene expression.

NOL12 is also of interest as a potential drug target. One way to target NOL12 is through inhibition of its activity, which could lead to decreased levels of RNA being produced. This could make NOL12 a useful biomarker for monitoring the effectiveness of drugs that are designed to inhibit its activity.

Another approach to targeting NOL12 is through competition for specific interactions with co-regulated proteins. This is suggested by the fact that NOL12 is able to interact with the protein known as RNA-binding protein (RBP) and that this interaction may play a role in regulating gene expression. Therefore, drugs that are able to compete with NOL12 for RBP interactions could be expected to have an impact on gene expression.

In conclusion, Nucleolar protein 12 (NOL12) is a unique protein that is expressed in various cell types and is thought to play a role in the regulation of gene expression. Its potential as a drug target is high, and research is ongoing to determine its full function and to explore its potential as a means of treating a variety of diseases.

Protein Name: Nucleolar Protein 12

Functions: May bind to 28S rRNA

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