MIR8084: A Potential Drug Target and Biomarker for Cancer (G102467005)
MIR8084: A Potential Drug Target and Biomarker for Cancer
MicroRNA (miRNA) 8084 is a non-coding RNA molecule that has been identified as a potential drug target and biomarker for various diseases, including cancer. MIR8084 is a part of the miRNA-21 (miR-21) family, which consists of 21 non-coding RNAs that have been shown to play important roles in various biological processes.
The miR-21 family of RNAs consists of four isoforms: miR-21-1, miR-21-2, miR-21-3, and miR-21-4. MIR8084 is the fifth isoform in the miR-21 family. It is a 24.3-nt RNA molecule that contains 195 amino acid residues. MIR8084 is predominantly expressed in the brain and is also found in other tissues, including muscle, heart, liver, and kidney.
MIR8084 has been shown to play a role in various biological processes, including cell growth, apoptosis (programmed cell death), and metabolism. It is also involved in the regulation of cellular processes that are important for cancer development, such as the development of neural stem cells, the regulation of angiogenesis (the formation of new blood vessels), and the regulation of immune cells.
One of the most promising aspects of MIR8084 is its potential as a drug target. MIR8084 has been shown to interact with several protein targets, including the transcription factor PDGF-BB, the protein SMAD4, and the protein NF-kappa-B. These interactions suggest that MIR8084 may be a useful target for drugs that are designed to modulate these protein targets.
In addition to its potential as a drug target, MIR8084 has also been shown to be a potential biomarker for various diseases, including cancer. For example, studies have shown that MIR8084 is downregulated in various types of cancer, including breast, ovarian, and prostate cancer. This suggests that MIR8084 may be a useful biomarker for these diseases.
Another promising aspect of MIR8084 is its expression pattern in various tissues and organs. Studies have shown that MIR8084 is expressed in a variety of tissues, including the brain, muscle, heart, liver, and kidney. This suggests that it may be a useful target for drugs that are designed to modulate its expression in these tissues.
In conclusion, MIR8084 is a non-coding RNA molecule that has been identified as a potential drug target and biomarker for various diseases, including cancer. Its interaction with protein targets and its expression pattern in various tissues suggest that it may be a useful target for drugs that are designed to modulate its activity. Further research is needed to fully understand the role of MIR8084 in these diseases and to develop effective treatments.
Protein Name: MicroRNA 8084
More Common Targets
MIR8085 | MIR8087 | MIR8088 | MIR8089 | MIR8485 | MIR873 | MIR874 | MIR875 | MIR876 | MIR877 | MIR885 | MIR887 | MIR888 | MIR889 | MIR890 | MIR891A | MIR891B | MIR892A | MIR892B | MIR892C | MIR9-1 | MIR9-1HG | MIR9-2 | MIR9-3 | MIR9-3HG | MIR920 | MIR921 | MIR922 | MIR924 | MIR924HG | MIR92A1 | MIR92A2 | MIR92B | MIR93 | MIR933 | MIR934 | MIR935 | MIR936 | MIR937 | MIR938 | MIR939 | MIR940 | MIR941-1 | MIR941-2 | MIR941-3 | MIR941-4 | MIR941-5 | MIR942 | MIR943 | MIR944 | MIR95 | MIR96 | MIR98 | MIR99A | MIR99AHG | MIR99B | MIRLET7 | MIRLET7A1 | MIRLET7A2 | MIRLET7A3 | MIRLET7B | MIRLET7BHG | MIRLET7C | MIRLET7D | MIRLET7E | MIRLET7F1 | MIRLET7F2 | MIRLET7G | MIRLET7I | MIS12 | MIS12 complex | MIS18A | MIS18A-AS1 | MIS18BP1 | MISFA | MISP | MISP3 | MITD1 | MITF | Mitochondrial complex I assembly complex | Mitochondrial import inner membrane translocase 23 (TIM23) complex | Mitochondrial inner membrane protease complex | Mitochondrial membrane ATP synthase | Mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) | Mitochondrial pyruvate carrier complex (MPC) | Mitochondrial RNA processing endoribonuclease | Mitofilin Complex | Mitofusin | Mitogen-Activated Protein Kinase | Mitogen-activated protein kinase (JNK) | Mitogen-Activated Protein Kinase (MAP Kinase)-Activated Protein Kinase | Mitogen-Activated Protein Kinase Kinase Kinase (MAP3K) | Mitogen-activated protein kinase p38 (MAPK p38) | MITRAC complex | MIX23 | MIXL1 | MKI67 | MKKS | MKLN1 | MKLN1-AS