MIS12: A Potential Drug Target Or Biomarker (G79003)

Target Name: MIS12

NCBI ID: G79003

MIS12: A Potential Drug Target Or Biomarker

MIS12, also known as homolog of yeast Mis12, is a protein that is expressed in the yeast species Saccharomyces cerevisiae. MIS12 is known for its role in the regulation of gene expression in the yeast cell. It is a key regulator of the genes involved in the synthesis of the protein copine, which is a key component of cell walls.

MIS12 is a transmembrane protein that is expressed in the cytoplasm of the yeast cell. It plays a role in the regulation of gene expression by binding to specific DNA sequences in the genome. It is known to interact with the transcription factors known as TFAP and SWI/SNF, which are responsible for the regulation of gene expression in the yeast cell.

One of the functions of MIS12 is to regulate the expression of genes involved in the synthesis of the cell wall. The cell wall is an important component of the yeast cell, and it plays a vital role in the mechanical stability of the cell. The synthesis of the cell wall is a complex process that is controlled by multiple genes, including MIS12.

MIS12 is also involved in the regulation of the growth and differentiation of yeast cells. It plays a role in the regulation of cell size and shape, as well as the development of cell processes such as budding and fragmentation. In addition, MIS12 is involved in the regulation of the interactions between cells in the yeast culture, which is important for the growth and proliferation of the yeast cells.

MIS12 is a protein that is of interest as a drug target or biomarker. Its involvement in the regulation of cell wall synthesis and growth makes it a potential target for drugs that are designed to interfere with these processes. For example, drugs that inhibit the activity of MIS12 could be useful in the treatment of conditions such as cancer, where the growth and development of cells is uncontrolled. In addition, MIS12 may be used as a biomarker to monitor the effectiveness of drugs that are designed to interfere with its function.

In conclusion, MIS12 is a protein that is of interest as a drug target or biomarker. Its involvement in the regulation of cell wall synthesis and growth makes it a potential target for drugs that are designed to interfere with these processes. In addition, MIS12 may be used as a biomarker to monitor the effectiveness of drugs that are designed to interfere with its function. Further research is needed to fully understand the role of MIS12 in the regulation of gene expression in the yeast cell, and to determine its potential as a drug target or biomarker.

Protein Name: MIS12 Kinetochore Complex Component

Functions: Part of the MIS12 complex which is required for normal chromosome alignment and segregation and for kinetochore formation during mitosis (PubMed:12515822, PubMed:15502821, PubMed:16585270). Essential for proper kinetochore microtubule attachments (PubMed:23891108)

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