Target Name: MKRN3
NCBI ID: G7681
Other Name(s): ZFP127 | D15S9 | RING-type E3 ubiquitin transferase makorin-3 | zinc finger protein 127 | MKRN3_HUMAN | Makorin-3 | CPPB2 | OTTHUMP00000159436 | MGC88288 | Probable E3 ubiquitin-protein ligase makorin-3 | makorin ring finger protein 3 | RING finger protein 63 | Zinc finger protein 127 | ZNF127 | Makorin ring finger protein 3 | RNF63

MKRN3 (ZFP127) as A Cancer Treatment Potential Drug Target

MKRN3 (ZFP127) is a gene that has been identified as a potential drug target or biomarker for the treatment of various diseases, including cancer. The gene is located on chromosome 6 and encodes for a protein known as ZFP127. ZFP127 is a transcription factor that plays a role in the regulation of gene expression and has been shown to be involved in a number of cellular processes, including cell growth, differentiation, and survival.

One of the key features of ZFP127 is its ability to form a complex with other transcription factors, including NF-kappa-B, p53, andCREB. This interaction between ZFP127 and these transcription factors is thought to play a role in the regulation of gene expression and the control of cellular processes such as cell growth, differentiation, and survival.

In addition to its role in transcription, ZFP127 has also been shown to play a role in the regulation of protein translation, which is the process by which proteins are synthesized from their amino acid sequence. This interaction between ZFP127 and protein translation factors is thought to be important for the regulation of cellular processes such as cell growth and survival.

The potential drug target status of ZFP127 is based on several factors. First, the gene has been shown to be involved in the regulation of cellular processes that are often disrupted in cancer, such as cell growth, differentiation, and survival. Second, the gene has been shown to play a role in the regulation of transcription, which is a critical process in the regulation of gene expression and the development of cancer.

Finally, ZFP127 has also been shown to interact with other transcription factors, including NF-kappa-B, p53, andCREB. This interaction with these transcription factors is thought to play a role in the regulation of gene expression and the development of cancer.

In conclusion, MKRN3 (ZFP127) is a gene that has been identified as a potential drug target or biomarker for the treatment of various diseases, including cancer. The gene is involved in the regulation of cellular processes such as cell growth, differentiation, and survival and has been shown to interact with other transcription factors that play a role in the development of cancer. Further research is needed to determine the full scope of ZFP127's potential as a drug target or biomarker.

Protein Name: Makorin Ring Finger Protein 3

Functions: E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins

More Common Targets

MKRN4P | MKRN7P | MKRN9P | MKS1 | MKX | MLANA | MLC1 | MLEC | MLF1 | MLF1-DT | MLF2 | MLH1 | MLH3 | MLIP | MLIP-AS1 | MLKL | MLLT1 | MLLT10 | MLLT10P1 | MLLT11 | MLLT3 | MLLT6 | MLN | MLNR | MLPH | MLST8 | MLX | MLXIP | MLXIPL | MLYCD | MMAA | MMAB | MMACHC | MMADHC | MMADHC-DT | MMD | MMD2 | MME | MMEL1 | MMGT1 | MMP | MMP1 | MMP10 | MMP11 | MMP12 | MMP13 | MMP14 | MMP15 | MMP16 | MMP17 | MMP19 | MMP2 | MMP2-AS1 | MMP20 | MMP20-AS1 | MMP21 | MMP23A | MMP23B | MMP24 | MMP24-AS1-EDEM2 | MMP24OS | MMP25 | MMP25-AS1 | MMP26 | MMP27 | MMP28 | MMP3 | MMP7 | MMP8 | MMP9 | MMRN1 | MMRN2 | MMS19 | MMS22L | MMS22L-TONSL complex | MMUT | MMXD complex | MN1 | MNAT1 | MND1 | MNDA | MNS1 | MNT | MNX1 | MNX1-AS1 | MOAP1 | MOB1A | MOB1B | MOB2 | MOB3A | MOB3B | MOB3C | MOB4 | MOBP | MOCOS | MOCS1 | MOCS2 | MOCS2-DT | MOCS3 | MOG