MMP24-AS1-EDEM2: A Potential Drug Target and Biomarker (G111089941)

Target Name: MMP24-AS1-EDEM2

NCBI ID: G111089941

Other Name(s): EDEM2_HUMAN | ER degradation-enhancing alpha-mannosidase-like protein 2 | MMP24-AS1-EDEM2 readthrough

MMP24-AS1-EDEM2: A Potential Drug Target and Biomarker

MMP24 is a protein that plays a crucial role in the regulation of cell migration and invasion. It is a member of the integrin complex, which is responsible for cell adhesion and migration. One of its subtypes, MMP24-AS1, has been shown to participate in several cellular processes, including the development and progression of cancer. Similarly, the EDEM2 gene has been linked to the development of various diseases, including cancer.

The MMP24-AS1-EDEM2 system has been identified as a potential drug target by several studies. First, researchers found that MMP24-AS1 was overexpressed in various cancer types, including breast, ovarian, and colorectal cancers. Second, they found that overexpression of MMP24-AS1 was associated with increased cancer cell migration and invasion. Third, they found that inhibition of MMP24-AS1 reduced the migration and invasion of cancer cells.

Furthermore, researchers have identified EDEM2 as a potential biomarker for cancer. They found that patients with various types of cancer had lower levels of EDEM2 than healthy cells. They also found that cancer cells with higher EDEM2 levels were more resistant to chemotherapy and radiation treatment.

The MMP24-AS1-EDEM2 system is a complex that has not yet been fully understood. However, it is clear that it is involved in several important cellular processes that are related to cancer development and progression. As such, it is a promising target for drug development. Researchers are currently working to identify small molecules that can inhibit MMP24-AS1 and increase EDEM2 levels in cancer cells, with the goal of developing a new treatment for various types of cancer.

In conclusion, MMP24-AS1-EDEM2 is a promising drug target and biomarker for cancer. Further research is needed to fully understand its role in cancer development and progression. By identifying small molecules that can inhibit MMP24-AS1 and increase EDEM2 levels in cancer cells, researchers may be able to develop new treatments for various types of cancer.

Protein Name: MMP24-AS1-EDEM2 Readthrough

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