MPP4: Key Regulator of The Proteasome (G58538)

Target Name: MPP4

NCBI ID: G58538

MPP4: Key Regulator of The Proteasome

MPP4, or menin-proteasome protein 4, is a protein that is expressed in various tissues throughout the body. It is a key regulator of the proteasome, a complex protein that helps to break down and remove damaged or unnecessary proteins from the body. Mutations in the MPP4 gene have been linked to a number of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. As a drug target, MPP4 has the potential to be developed into a new treatment for a variety of conditions.

The proteasome is a complex protein that is responsible for breaking down and removing damaged or unnecessary proteins from the body. It is made up of a core protein that is surrounded by a series of smaller proteins that work together to break down the protein. The MPP4 protein is one of the smaller proteins that is involved in the proteasome. It is made up of four subunits that are held together by a series of interactions between the subunits.

MPP4 is involved in the regulation of the proteasome by helping to ensure that it is properly assembled and that it has the correct level of activity. It does this by playing a role in the formation of the nucleotide-protein complex, which is the starting point for the proteasome. The nucleotide-protein complex is made up of the protein alpha-2 macroglobulin (伪2M), which is the core protein of the proteasome, and the protein light chain, which is one of the smaller proteins that is involved in the formation of the complex.

MPP4 helps to ensure that the nucleotide-protein complex is properly assembled by helping to connect the subunits of the protein. It does this by playing a role in the regulation of the activity of the enzyme alpha-2A, which is responsible for connecting the subunits of the protein. alpha-2A is a protein that is expressed in various tissues throughout the body and is involved in the regulation of a wide range of cellular processes.

MPP4 is also involved in the regulation of the proteasome by helping to ensure that it has the correct level of activity. It does this by playing a role in the regulation of the activity of the enzyme alpha-2B, which is responsible for activating the proteasome . alpha-2B is a protein that is expressed in various tissues throughout the body and is involved in the regulation of a wide range of cellular processes.

MPP4 is also involved in the regulation of the proteasome by helping to ensure that it is properly assembled. It does this by playing a role in the regulation of the activity of the enzyme alpha-2C, which is responsible for connecting the subunits of the protein . alpha-2C is a protein that is expressed in various tissues throughout the body and is involved in the regulation of a wide range of cellular processes.

MPP4 is also involved in the regulation of the proteasome by helping to ensure that it has the correct level of activity. It does this by playing a role in the regulation of the activity of the enzyme alpha-2D, which is responsible for activating the proteasome . alpha-2D is a protein that is expressed in various tissues throughout the body and is involved in the regulation of a wide range of cellular processes.

In conclusion, MPP4 is a key regulator of the proteasome, a complex protein that is responsible for breaking down and removing damaged or unnecessary proteins from the body. Mutations in the MPP4 gene have been linked to a number of diseases, including cancer, neurodegenerative diseases , and autoimmune disorders. As a drug target, MPP4 has the potential to be developed into a new treatment for a variety of conditions.

Protein Name: MAGUK P55 Scaffold Protein 4

Functions: May play a role in retinal photoreceptors development

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