Target Name: MOGS
NCBI ID: G7841
Other Name(s): MOGS variant 1 | epididymis secretory sperm binding protein | Glucosidase I | MOGS_HUMAN | OTTHUMP00000202621 | Mannosyl-oligosaccharide glucosidase (isoform 2) | Mannosyl-oligosaccharide glucosidase (isoform 1) | Trimming glucosidase I | Glc3Man9NAc2 oligosaccharide glucosidase | OTTHUMP00000202624 | Mannosyl-oligosaccharide glucosidase, transcript variant 1 | OTTHUMP00000202623 | DER7 | CDG2B | processing A-glucosidase I | Processing A-glucosidase I | MOGS variant 2 | mannosyl-oligosaccharide glucosidase | CWH41 | Mannosyl-oligosaccharide glucosidase | GCS1 | glucosidase I | Mannosyl-oligosaccharide glucosidase, transcript variant 2 | OTTHUMP00000202622

MOGS: A Protein with Potential Therapeutic Applications

MOGS (MOGS variant 1) is a protein that is expressed in various tissues of the body, including the brain, pancreas, and testes. It is a member of the MOG family of proteins, which are known for their role in cell signaling and inflammation. While the exact function of MOGS is not yet fully understood, it is possible that it may be a drug target or biomarker for various diseases.

One of the key features of MOGS is its role in the regulation of inflammation. MOGS has been shown to play a key role in the production of inflammatory cytokines, which are proteins that play a central role in the inflammatory response. These cytokines can help to recruit and activate immune cells, which can contribute to the development and progression of a wide range of inflammatory diseases, including autoimmune disorders, cancer, and cardiovascular disease.

Another potential function of MOGS is its role in cell signaling. MOGS has been shown to play a key role in the regulation of cell signaling pathways, which are the channels through which cells communicate with one another. These signaling pathways can help to regulate a wide range of cellular processes, including cell growth, differentiation, and inflammation. MOGS has been shown to play a key role in the regulation of the JAK/STAT signaling pathway, which is involved in the regulation of immune cell function and inflammation.

In addition to its potential role in cell signaling and inflammation, MOGS is also of interest as a potential drug target. By targeting MOGS with small molecules or other therapeutic agents, researchers may be able to reduce the production of inflammatory cytokines and improve the regulation of cell signaling pathways. This could have a wide range of potential therapeutic applications, including the treatment of a wide range of inflammatory diseases, including autoimmune disorders, cancer, and cardiovascular disease.

Overall, MOGS (MOGS variant 1) is a protein that is of great interest for its potential as a drug target or biomarker. While further research is needed to fully understand its function and potential therapeutic applications, its potential as a regulator of cell signaling and inflammation makes it a promising area of study.

Protein Name: Mannosyl-oligosaccharide Glucosidase

Functions: Cleaves the distal alpha 1,2-linked glucose residue from the Glc(3)Man(9)GlcNAc(2) oligosaccharide precursor in a highly specific manner

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