Target Name: MOCS1
NCBI ID: G4337
Other Name(s): GTP 3',8-cyclase | Molybdenum cofactor biosynthesis protein A | Molybdenum cofactor biosynthesis protein 1 isoform 7 | MOCOD | Molybdenum cofactor synthesis 1, transcript variant 7 | molybdenum cofact

MOCS1: Key Enzyme in GPCR Signaling Pathway

MOCS1 (GTP 3',8-cyclase) is a protein that is expressed in various tissues throughout the body. It is a key enzyme in the intracellular signaling pathway known as the G-protein-coupled receptor (GPCR) signaling pathway. MOCS1 plays a crucial role in the regulation of a wide range of physiological processes, including sensory perception, neurotransmitter signaling, and cell survival.

MOCS1 is a member of the GPCR signaling pathway, which is a complex network of proteins that regulate the interaction between GPCRs and their ligands. The GPCR signaling pathway is involved in many cellular processes that are essential for life, including but not limited to:

* Cell survival and proliferation
* Sensory perception and neurotransmission
* Hormonal signaling
*Immune response

MOCS1 is a key enzyme in the GPCR signaling pathway because it is involved in the regulation of several critical events that are required for the proper functioning of the pathway. It plays a crucial role in the regulation of the activity of several GPCRs, including but not limited to:

*尾2 adrenergic receptor (尾2AR)
*尾1 adrenergic receptor (尾1AR)
*Neurotransmitter receptors

MOCS1 is also involved in the regulation of the phosphorylation of several key protein substrates, including but not limited to:

*Ca2+ ion
*CaM
*Phosphatidylinositol

MOCS1 is a protein that has been identified as a potential drug target for several diseases, including but not limited to:

*Attention deficit hyperactivity disorder (ADHD)
*Nausea and vomiting (NAV)
*Dementia
*Parkinson's disease

MOCS1 has also been identified as a potential biomarker for several diseases, including but not limited to:

*Dementia
*Parkinson's disease
*Alzheimer's disease

MOCS1 is a versatile protein that plays a critical role in the regulation of many physiological processes that are essential for the proper functioning of the body. It is a potential drug target and biomarker for several diseases, including but not limited to ADHD, NAV, dementia , and Parkinson's disease. Further research is needed to fully understand the role of MOCS1 in the regulation of these diseases and to develop effective therapies.

Protein Name: Molybdenum Cofactor Synthesis 1

Functions: Isoform MOCS1A and isoform MOCS1B probably form a complex that catalyzes the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP). MOCS1A catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate and MOCS1B catalyzes the subsequent conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cPMP

More Common Targets

MOCS2 | MOCS2-DT | MOCS3 | MOG | MOGAT1 | MOGAT2 | MOGAT3 | MOGS | MOK | MON1A | MON1B | MON2 | Monoamine oxidase (MAO) | Monoamine Transporter (MAT) | MORC1 | MORC2 | MORC2-AS1 | MORC3 | MORC4 | MORF4 | MORF4L1 | MORF4L1P1 | MORF4L1P3 | MORF4L1P7 | MORF4L2 | MORF4L2-AS1 | MORN1 | MORN2 | MORN3 | MORN4 | MORN5 | MOS | MOSMO | MOSPD1 | MOSPD2 | MOSPD3 | MOV10 | MOV10L1 | MOXD1 | MOXD2P | MPC1 | MPC2 | MPDU1 | MPDU1-AS1 | MPDZ | MPEG1 | MPG | MPHOSPH10 | MPHOSPH10P1 | MPHOSPH6 | MPHOSPH8 | MPHOSPH9 | MPI | MPIG6B | MPL | MPLKIP | MPND | MPO | MPP1 | MPP2 | MPP3 | MPP4 | MPP7 | MPPE1 | MPPED1 | MPPED2 | MPPED2-AS1 | MPRIP | MPST | MPTX1 | MPV17 | MPV17L | MPV17L2 | MPZ | MPZL1 | MPZL2 | MPZL3 | MR1 | MRAP | MRAP2 | MRAS | MRC1 | MRC2 | MRE11 | MREG | MRFAP1 | MRFAP1L1 | MRGBP | MRGPRD | MRGPRE | MRGPRF | MRGPRF-AS1 | MRGPRG | MRGPRX1 | MRGPRX2 | MRGPRX3 | MRGPRX4 | MRI1 | MRLN | MRM1