Target Name: MOB4
NCBI ID: G25843
Other Name(s): MGC12264 | MOB1, Mps One Binder kinase activator-like 3 | Mob3 | MOB-like protein phocein (isoform 1) | CGI-95 | MOB3 | Phocein | Mob1 homolog 3 | preimplantation protein 3 | MOB-like protein phocein | PHOCN_HUMAN | MOB4 variant 1 | Preimplantation protein 3 | Mps one binder kinase activator-like 3 | MOB family member 4, phocein | MOBKL3 | MOB1 | Phocein, Mob-like protein | Class II mMOB1 | phocein, Mob-like protein | class II mMOB1 | 2C4D | MOB family member 4, phocein, transcript variant 1 | mob1 homolog 3 | Mps One Binder kinase activator-like 3 | PREI3 | PHOCN

MOB4: A Potential Drug Target and Biomarker

MOB4 (MGC12264) is a protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. It is a member of the heat shock protein (HSP) family, which are proteins that are expressed in response to increased temperatures or other forms of stress.

One of the unique features of MOB4 is its ability to interact with other proteins that are expressed in the brain, including the protein known as heat shock protein-70 (HSP70). This interaction between MOB4 and HSP70 has been shown to play a role in the regulation of a variety of cellular processes, including the regulation of inflammation, stress response, and cell survival.

In addition to its role in cellular signaling, MOB4 is also of interest as a potential drug target. Its interaction with HSP70 has led to the development of small molecules that can inhibit the activity of HSP70, which could be useful for treating a variety of diseases. For example, these small molecules have been shown to be effective in treating a variety of neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease.

Another potential application of MOB4 is as a biomarker for certain diseases. Its interaction with HSP70 has led to the development of a variety of diagnostic tests that can detect changes in the levels of HSP70 in certain tissues, which could be used as markers for disease. For example, these tests have been shown to be effective in the diagnosis of neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease.

Overall, MOB4 is a protein that has significant potential as a drug target and biomarker. Its interaction with HSP70 and its ability to regulate cellular processes make it an attractive target for small molecule inhibitors. Further research is needed to fully understand the role of MOB4 in cellular signaling and its potential as a drug and biomarker.

Protein Name: MOB Family Member 4, Phocein

Functions: May play a role in membrane trafficking, specifically in membrane budding reactions

More Common Targets

MOBP | MOCOS | MOCS1 | MOCS2 | MOCS2-DT | MOCS3 | MOG | MOGAT1 | MOGAT2 | MOGAT3 | MOGS | MOK | MON1A | MON1B | MON2 | Monoamine oxidase (MAO) | Monoamine Transporter (MAT) | MORC1 | MORC2 | MORC2-AS1 | MORC3 | MORC4 | MORF4 | MORF4L1 | MORF4L1P1 | MORF4L1P3 | MORF4L1P7 | MORF4L2 | MORF4L2-AS1 | MORN1 | MORN2 | MORN3 | MORN4 | MORN5 | MOS | MOSMO | MOSPD1 | MOSPD2 | MOSPD3 | MOV10 | MOV10L1 | MOXD1 | MOXD2P | MPC1 | MPC2 | MPDU1 | MPDU1-AS1 | MPDZ | MPEG1 | MPG | MPHOSPH10 | MPHOSPH10P1 | MPHOSPH6 | MPHOSPH8 | MPHOSPH9 | MPI | MPIG6B | MPL | MPLKIP | MPND | MPO | MPP1 | MPP2 | MPP3 | MPP4 | MPP7 | MPPE1 | MPPED1 | MPPED2 | MPPED2-AS1 | MPRIP | MPST | MPTX1 | MPV17 | MPV17L | MPV17L2 | MPZ | MPZL1 | MPZL2 | MPZL3 | MR1 | MRAP | MRAP2 | MRAS | MRC1 | MRC2 | MRE11 | MREG | MRFAP1 | MRFAP1L1 | MRGBP | MRGPRD | MRGPRE | MRGPRF | MRGPRF-AS1 | MRGPRG | MRGPRX1 | MRGPRX2 | MRGPRX3 | MRGPRX4