Target Name: GLRX3
NCBI ID: G10539
Other Name(s): testicular tissue protein Li 75 | glutaredoxin 3 | Thioredoxin-like 2 | PKCq-interacting protein | Glutaredoxin-3 | PICOT | Glutaredoxin-3 (isoform 1) | thioredoxin-like protein 2 | Glutaredoxin 4 | PKC-interacting cousin of thioredoxin | FLJ11864 | TXNL2 | PKC-theta-interacting protein | Glutaredoxin 3, transcript variant 2 | TXNL3 | GRX3 | bA500G10.4 | GLRX4 | GLRX3_HUMAN | GRX4 | glutaredoxin 4 | OTTHUMP00000020747 | GLRX3 variant 2 | Thioredoxin-like protein 2

GLRX3: A Potential Drug Target and Biomarker for Testicular Tissue Protein Li 75

Introduction

Testicular tissue protein Li 75 is a key regulator of many biological processes, including germ cell generation and regeneration. It plays an important role in humans, but also in some tumors. GLRX3 is a Li 75-related protein that may play an important role in tumor occurrence and development. This article will discuss the properties of GLRX3 as a potential drug target and biomarker.

Biological functions of GLRX3

GLRX3 is a protein highly expressed in a variety of human tissues. It plays a role in a variety of physiological processes, including germ cell genesis and nervous system development. GLRX3 is also closely related to Li 75 and exerts biological functions under the action of Li 75.

The role of GLRX3 in tumorigenesis and development

Many tumor cells express GLRX3 and play an important role in tumor occurrence and development. The expression level of GLRX3 is positively correlated with tumor growth and invasion ability. Studies have found that the expression level of GLRX3 is directly proportional to the invasion ability of tumors and has nothing to do with the metastasis ability of tumors.

GLRX3 can also be used as a potential target in tumor treatment. The use of GLRX3 antagonists can inhibit the growth and invasion of tumor cells, thereby improving the efficiency of tumor treatment. GLRX3 antagonists can also reduce the metastasis of tumor cells, thereby improving the survival rate of tumor patients.

Biological mechanism of GLRX3

As a protein, GLRX3's biological mechanism plays a role in tumor occurrence and development in various ways. GLRX3 can regulate the generation and differentiation of germ cells, thereby controlling the growth of tumor cells. GLRX3 can also participate in the development and function of the nervous system, thereby affecting tumor occurrence and development.

The relationship between GLRX3 and Li 75

GLRX3 is closely related to Li 75 and exerts its biological functions under the action of Li 75. Li 75 is a protein that can be expressed in a variety of tumors and plays an important role in tumor occurrence and development. Studies have found that GLRX3 can interact with Li 75 to exert biological functions.

Clinical applications of GLRX3

As a protein, GLRX3 has great potential as a target for tumor treatment. Currently, GLRX3 antagonists have been used in clinical research and have made certain progress. Future studies can further explore the application of GLRX3 in tumor treatment, especially its role in inhibiting the growth and invasion of tumor cells.

in conclusion

GLRX3 is a protein closely related to Li 75 and may play an important role in tumor occurrence and development. GLRX3 can be used as a drug target and as a biomarker for tumor treatment. Future studies can further explore the application of GLRX3 in tumor treatment, especially its role in inhibiting the growth and invasion of tumor cells.

Protein Name: Glutaredoxin 3

Functions: Together with BOLA2, acts as a cytosolic iron-sulfur (Fe-S) cluster assembly factor that facilitates [2Fe-2S] cluster insertion into a subset of cytosolic proteins (PubMed:26613676, PubMed:27519415). Acts as a critical negative regulator of cardiac hypertrophy and a positive inotropic regulator (By similarity). Required for hemoglobin maturation (PubMed:23615448). Does not possess any thyoredoxin activity since it lacks the conserved motif that is essential for catalytic activity

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GLRX3P2 | GLRX5 | GLS | GLS2 | GLT1D1 | GLT6D1 | GLT8D1 | GLT8D2 | GLTP | GLTPD2 | Glucagon-like peptide receptor (GLP-R) | Glucosidase | GLUD1 | GLUD1P2 | GLUD1P3 | GLUD2 | GLUL | GLULP2 | GLULP4 | Glutamate receptor | Glutamate Receptor Ionotropic | Glutamate Receptor Ionotropic AMPA Receptor | Glutamate Transporter | Glutaminase | Glutathione peroxidase | Glutathione S-Transferase (GST) | GLYAT | GLYATL1 | GLYATL1B | GLYATL2 | GLYATL3 | GLYCAM1 | Glycine receptor | Glycogen phosphorylase | Glycogen synthase | Glycogen synthase kinase 3 (GSK-3) | Glycoprotein hormone | Glycoprotein Hormone Receptor | GLYCTK | Glycylpeptide N-tetradecanoyltransferase | Glypican | GLYR1 | GM-CSF Receptor (GM-CSF-R) | GM1 ganglioside | GM2A | GM2AP1 | GM2AP2 | GMCL1 | GMCL2 | GMDS | GMDS-DT | GMEB1 | GMEB2 | GMFB | GMFG | GMIP | GML | GMNC | GMNN | GMPPA | GMPPB | GMPR | GMPR2 | GMPS | GNA11 | GNA12 | GNA13 | GNA14 | GNA15 | GNAI1 | GNAI2 | GNAI3 | GNAL | GNAO1 | GNAO1-DT | GNAQ | GNAS | GNAS-AS1 | GNAT1 | GNAT2 | GNAT3 | GNAZ | GNB1 | GNB1L | GNB2 | GNB3 | GNB4 | GNB5 | GNE | GNG10 | GNG11 | GNG12 | GNG12-AS1 | GNG13 | GNG2 | GNG3 | GNG4 | GNG5 | GNG5P5 | GNG7