SMYD4: A Protein Involved in Intracellular Signaling Pathways and Drug Targets

Target Name: SMYD4

NCBI ID: G114826

Other Name(s): SET and MYND domain-containing protein 4 | KIAA1936 | ZMYND21 | SET and MYND domain containing 4 | SMYD4_HUMAN

SMYD4: A Protein Involved in Intracellular Signaling Pathways and Drug Targets

SMYD4 (SET and MYND domain-containing protein 4) is a protein that is expressed in a wide range of tissues throughout the body. It is a member of the SMYD family of proteins, which are known for their role in intracellular signaling pathways. SMYD4 is characterized by the presence of a SET domain and a MYND domain, as well as a number of other unique features.

SMYD4 is involved in a number of different cellular processes, including cell signaling, DNA replication, and metabolism. It is a key regulator of the myeloid differentiation antigen (MDA) pathway, which is involved in the regulation of cellular responses to stress and damage. SMYD4 is also involved in the regulation of cell growth and in the development of cancer.

In addition to its role in intracellular signaling pathways, SMYD4 is also a potential drug target. Its involvement in a number of cellular processes makes it an attractive target for small molecules, which can be used to inhibit its activity or to activate its targets. Additionally, its well-characterized structure and the fact that it is expressed in a wide range of tissues make it an attractive target for drug development.

SMYD4 is also a potential biomarker for a number of diseases. Its involvement in the myeloid differentiation antigen pathway makes it an attractive target for diagnostic tests that are used to monitor the activity of this pathway. Additionally, its involvement in cell signaling and metabolism makes it a potential target for diseases that are characterized by the over-expression of SMYD4.

In conclusion, SMYD4 is a protein that is involved in a number of different cellular processes and is a potential drug target. Its well-characterized structure and its expression in a wide range of tissues make it an attractive target for small molecules and diagnostic tests. Further research is needed to fully understand its role in cellular processes and its potential as a drug target.

Protein Name: SET And MYND Domain Containing 4

Functions: Plays a critical role in cardiac development (PubMed:30110327). Acts as a key epigenetic regulator of gene expression during cardiac development via its dual activities as a methyltransferase and negative regulator of HDAC1 (By similarity)

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