Target Name: DSC1
NCBI ID: G1823
Other Name(s): CDHF1 | Desmocollin 1, transcript variant Dsc1b | desmocollin 1 | Desmocollin 1, transcript variant Dsc1a | DG2/DG3 | DSC1 variant Dsc1a | DSC1 variant Dsc1b | Desmocollin-1 | DSC1_HUMAN | desmosomal glycoprotein 2/3 | cadherin family member 1 | Desmosomal glycoprotein 2/3 | Cadherin family member 1

DSC1: A Drug Target / Disease Biomarker

DSC1 (Dipeptidyl-L-Leucine) is a drug target and a biomarker that has been shown to have a role in various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. Its unique structure and chemical properties make it an attractive target for drug development.

DSC1 is a small protein that is expressed in various tissues and cells in the body. It is composed of two distinct regions: an N-terminal region that contains a unique amino acid sequence, and a C-terminal region that contains a glycine-rich loop and a leucine side chain. The N-terminal region is known as the leucine-rich region or LRR, and it is the region that gives DSC1 its unique structure and its ability to interact with other proteins.

The LRR is a key region that contains several unique amino acids that are not found in other proteins. The most prominent of these amino acids is alanine, which is a polar amino acid that has a negatively charged side and a positively charged back. This structure gives DSC1 its electrostatic potential, which is important for its ability to interact with other proteins.

DSC1 has been shown to play a role in various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. For example, DSC1 has been shown to be involved in the development of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease. Studies have shown that DSC1 levels are decreased in the brains of individuals with these conditions, and that levels are increased in the brains of individuals who have the genes for these conditions.

DSC1 has also been shown to be involved in the development of cancer. Studies have shown that DSC1 is expressed in various types of cancer, and that it is involved in the development of cancer by promoting the growth and survival of cancer cells.

DSC1 has also been shown to be involved in autoimmune disorders. Studies have shown that DSC1 is involved in the development of autoimmune disorders, such as rheumatoid arthritis and multiple sclerosis.

In conclusion, DSC1 is a drug target and biomarker that has been shown to play a role in various diseases. Its unique structure and chemical properties make it an attractive target for drug development. Further research is needed to fully understand the role of DSC1 in these diseases and to develop effective treatments.

Protein Name: Desmocollin 1

Functions: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. May contribute to epidermal cell positioning (stratification) by mediating differential adhesiveness between cells that express different isoforms. Linked to the keratinization of epithelial tissues

More Common Targets

DSC2 | DSC3 | DSCAM | DSCAM-AS1 | DSCAML1 | DSCC1 | DSCR10 | DSCR4 | DSCR8 | DSCR9 | DSE | DSEL | DSEL-AS1 | DSG1 | DSG1-AS1 | DSG2 | DSG3 | DSG4 | DSN1 | DSP | DSP-AS1 | DSPP | DST | DST-AS1 | DSTN | DSTNP2 | DSTYK | DTD1 | DTD1-AS1 | DTD2 | DTHD1 | DTL | DTNA | DTNB | DTNB-AS1 | DTNBP1 | DTWD1 | DTWD2 | DTX1 | DTX2 | DTX2P1 | DTX2P1-UPK3BP1-PMS2P11 | DTX3 | DTX3L | DTX4 | DTYMK | Dual Specificity Mitogen-Activated Protein Kinase Kinase (MEK) | Dual specificity protein kinase (CLK) | Dual specificity protein tyrosine phosphatase | Dual-Specificity Tyrosine-(Y)-Phosphorylation Regulated Kinase 1 | DUBR | DUOX1 | DUOX2 | DUOXA1 | DUOXA2 | DUS1L | DUS2 | DUS3L | DUS4L | DUSP1 | DUSP10 | DUSP11 | DUSP12 | DUSP13 | DUSP14 | DUSP15 | DUSP16 | DUSP18 | DUSP19 | DUSP2 | DUSP21 | DUSP22 | DUSP23 | DUSP26 | DUSP28 | DUSP29 | DUSP3 | DUSP4 | DUSP5 | DUSP5P1 | DUSP6 | DUSP7 | DUSP8 | DUSP8P5 | DUSP9 | DUT | DUTP6 | DUX1 | DUX3 | DUX4 | DUX4L1 | DUX4L13 | DUX4L16 | DUX4L18 | DUX4L19 | DUX4L2 | DUX4L20 | DUX4L23 | DUX4L3 | DUX4L37