Potential Drug Target and Biomarker for OR9I1 (G219954)

Target Name: OR9I1

NCBI ID: G219954

Potential Drug Target and Biomarker for OR9I1

OR9I1 (Olfactory Receptor OR11-228) is a protein that is expressed in the olfactory system, which is responsible for the sense of smell. OR9I1 has been identified as a potential drug target and is a focus of research at the University of California, San Diego School of Medicine.

OR9I1 is a transmembrane protein that is expressed in the olfactory epithelium, which is the lining of the olfactory system. The olfactory epithelium is composed of two layers of cells: the outer layer is composed of sensory neurons, which transmit signals from the sense organs to the brain, and the inner layer is composed of supporting cells, which provide structural support to the sensory neurons.

OR9I1 is a member of the Olfactory Receptor family, which includes proteins that are responsible for transmitting signals from the sense organs to the brain. The Olfactory Receptor family has been identified as a potential drug target due to its involvement in the sense of smell.

Research has shown that changes in the level of OR9I1 have been associated with a range of neurological and psychiatric disorders, including Alzheimer's disease, Parkinson's disease, and depression. Additionally, altered levels of OR9I1 have also been observed in conditions such as cancer and neurodegenerative diseases.

Due to its potential as a drug target, OR9I1 has been the subject of intense research at the University of California, San Diego School of Medicine. Studies have shown that OR9I1 can be targeted with small molecules, such as those that bind to its extracellular domain. Additionally, preclinical studies have shown that targeting OR9I1 with small molecules has the potential to improve sensory function and reduce symptoms in animal models of neurological disorders.

In addition to its potential as a drug target, OR9I1 is also a potential biomarker for a range of neurological and psychiatric disorders. Studies have shown that altered levels of OR9I1 are associated with a range of disorders, including Alzheimer's disease, Parkinson's disease, and depression. Additionally, altered levels of OR9I1 have also been observed in conditions such as cancer and neurodegenerative diseases.

In conclusion, OR9I1 (Olfactory Receptor OR11-228) is a protein that is expressed in the olfactory system and has been identified as a potential drug target and biomarker for a range of neurological and psychiatric disorders. Further research is needed to fully understand its role in the sense of smell and its potential as a drug and biomarker.

Protein Name: Olfactory Receptor Family 9 Subfamily I Member 1

Functions: Odorant receptor

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