Understanding RCOR1: A Potential Drug Target and Biomarker (G23186)

Target Name: RCOR1

NCBI ID: G23186

Understanding RCOR1: A Potential Drug Target and Biomarker

RCOR1 (Registered Control of Risk) is a protein that is expressed in various tissues of the human body. It is a key regulator of cell proliferation and has been implicated in various diseases, including cancer. The RCOR1 gene has also been identified as a potential drug target and biomarker. In this article, we will discuss the RCOR1 protein, its functions, potential drug targets, and its potential as a biomarker for various diseases.

Function and Expression

RCOR1 is a 21-kDa protein that is expressed in various tissues of the human body, including muscle, liver, and kidney. It is primarily localized to the cytoplasm and has been shown to be involved in the regulation of cell proliferation, apoptosis, and autophagy. RCOR1 has been shown to play a role in the regulation of T cell development and has been implicated in the development of T-cell acute lymphoblastic leukemia.

Potential Drug Targets

RCOR1 has been identified as a potential drug target due to its involvement in various diseases. One of the main drug targets for RCOR1 is the regulation of cell proliferation. drugs that target RCOR1 have been shown to inhibit its function in cell proliferation and induce cell apoptosis. This has led to the potential for these drugs to be used in various diseases, including cancer.

Another potential drug target for RCOR1 is its role in the regulation of apoptosis. RCOR1 has been shown to play a role in the regulation of apoptosis and has been implicated in the development of various diseases, including neurodegenerative disorders. Drugs that target RCOR1 have been shown to be effective in treating these disorders.

In addition to its potential as a drug target, RCOR1 has also been identified as a potential biomarker for various diseases. Its expression has been shown to be associated with various diseases, including cancer, neurodegenerative disorders, and autoimmune diseases. This has led to the potential for RCOR1 to be used as a biomarker for these diseases and for monitoring disease progression.

Conclusion

In conclusion, RCOR1 is a protein that has been shown to play a role in various diseases, including cancer. Its expression has also been associated with various biomarkers. The potential drug targets for RCOR1 include the regulation of cell proliferation and apoptosis, making it an attractive target for drug development. Additionally, RCOR1 has also been identified as a potential biomarker for various diseases, which has the potential to revolutionize the field of diagnostic tests. Further research is needed to fully understand the functions and potential of RCOR1 as a drug target and biomarker.

Protein Name: REST Corepressor 1

Functions: Essential component of the BHC complex, a corepressor complex that represses transcription of neuron-specific genes in non-neuronal cells. The BHC complex is recruited at RE1/NRSE sites by REST and acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier. In the BHC complex, it serves as a molecular beacon for the recruitment of molecular machinery, including MeCP2 and SUV39H1, that imposes silencing across a chromosomal interval. Plays a central role in demethylation of Lys-4 of histone H3 by promoting demethylase activity of KDM1A on core histones and nucleosomal substrates. It also protects KDM1A from the proteasome. Component of a RCOR/GFI/KDM1A/HDAC complex that suppresses, via histone deacetylase (HDAC) recruitment, a number of genes implicated in multilineage blood cell development and controls hematopoietic differentiation

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