Understanding GAS8: Potential Drug Target Or Biomarker (G2622)

Target Name: GAS8

NCBI ID: G2622

Understanding GAS8: Potential Drug Target Or Biomarker

GAS8, also known as Growth arrest-specific protein 11, is a protein that is expressed in a variety of tissues and cells throughout the body. It is a non-coding RNA molecule that has been shown to play a role in cell growth, apoptosis, and other cellular processes. As a result, GAS8 has potential as a drug target or biomarker.

GAS8 is expressed in a variety of tissues, including muscle, heart, brain, and cancer. It is also highly expressed in the placenta, which is a vital organ that supports the growth and development of fetal cells. This suggests that GAS8 may be involved in the regulation of fetal growth and development.

One of the key functions of GAS8 is its role in cell apoptosis. Apoptosis is a natural process that is involved in the elimination of damaged or dysfunctional cells. In cancer, apoptosis can be triggered as a result of various factors, including exposure to chemotherapy drugs or radiation. By regulating apoptosis, GAS8 may have the potential to contribute to the development of more effective cancer treatments.

Another function of GAS8 is its role in cell growth. GAS8 has been shown to play a role in the regulation of cell proliferation, which is a critical process for the growth and development of tissues and organs.

GAS8 has also been shown to play a role in the regulation of cellular processes that are involved in the development and maintenance of tissues. For example, GAS8 has been shown to be involved in the regulation of cell adhesion, which is the process by which cells stick together to form tissues and organs.

In addition to its role in cell biology, GAS8 has also been shown to play a role in the regulation of cellular processes that are involved in the development and progression of diseases. For example, GAS8 has been shown to be involved in the regulation of the angiogenesis, which is the process by which new blood vessels are formed in the body. This is important for the development of many diseases, including cancer and cardiovascular disease.

GAS8 has also been shown to play a role in the regulation of cellular processes that are involved in the regulation of cellular signaling pathways. These signaling pathways are the channels through which cells communicate with one another and coordinate their activities.

GAS8 has been shown to play a role in the regulation of the Wnt signaling pathway, which is a critical pathway involved in the development and maintenance of tissues. This pathway is important for the development of many diseases, including cancer.

In conclusion, GAS8 is a protein that is expressed in a variety of tissues and cells throughout the body. It has been shown to play a role in a variety of cellular processes, including cell apoptosis, cell growth, and cellular signaling pathways. As a result, GAS8 has potential as a drug target or biomarker. Further research is needed to fully understand the role of GAS8 in these processes and to develop more effective treatments for diseases.

Protein Name: Growth Arrest Specific 8

Functions: Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. Plays an important role in the assembly of the N-DRC linker (By similarity). Plays dual roles at both the primary (or non-motile) cilia to regulate hedgehog signaling and in motile cilia to coordinate cilia movement. Required for proper motile cilia functioning (PubMed:26387594, PubMed:27120127, PubMed:27472056). Positively regulates ciliary smoothened (SMO)-dependent Hedgehog (Hh) signaling pathway by facilitating the trafficking of SMO into the cilium and the stimulation of SMO activity in a GRK2-dependent manner (By similarity)

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