LINC00928: A Potential Drug Target and Biomarker (G283761)

Target Name: LINC00928

NCBI ID: G283761

Other Name(s): long intergenic non-protein coding RNA 928 | Long intergenic non-protein coding RNA 928, transcript variant 1

LINC00928: A Potential Drug Target and Biomarker

LINC00928 is a long intergenic non-protein coding RNA (lncRNA) with a length of approximately 210 nucleotides. It is located between the genes HO-1 and IDH1 on chromosome 16 and is predicted to encode a protein with at least 60 amino acid residues.

LINC00928 is a non-coding RNA molecule that has been identified as a potential drug target and biomarker. The discovery of LINC00928 was made using a computational approach that involved the analysis of gene expression data from the Gene Expression Omnibus (GEO) database.

Based on the analysis of gene expression data, researchers found that LINC00928 was highly expressed in a variety of tissues and organs, including the brain, heart, and pancreas. The expression of LINC00928 was also highly correlated with the expression of other genes, including HO-1 and IDH1, which are both known to be involved in the development and progression of cancer.

In addition to its potential drug target properties, LINC00928 also has the potential to serve as a biomarker for cancer. The expression of LINC00928 has been observed in a variety of cancer types, including breast, ovarian, and prostate cancers. Additionally, LINC00928 has been shown to be downregulated in cancer cells, which suggests that it may be a potential therapeutic target.

The potential drug target properties of LINC00928 are based on its predicted protein sequence. The protein encoded by LINC00928 is predicted to have a molecular weight of approximately 60 kDa and to have four distinct functional domains: an N-terminal transmembrane domain, a cytoplasmic domain, a C-terminal T-loop domain, and a variable region.

The N-terminal transmembrane domain is thought to be involved in the regulation of cell signaling pathways and the cytoplasmic domain is involved in protein-protein interactions. The C-terminal T-loop domain is thought to be involved in the regulation of protein stability and the variable region is thought to contain the unique genetic information that gives the protein its unique structure.

Based on these predictions, LINC00928 is expected to have a variety of potential functions in different cellular processes, including the regulation of cell signaling pathways, the regulation of protein stability, and the regulation of gene expression.

In conclusion, LINC00928 is a long intergenic non-protein coding RNA that has been identified as a potential drug target and biomarker. Its unique protein sequence and its expression in a variety of tissues and organs make it a promising candidate for further study. Further research is needed to determine the exact function of LINC00928 in different cellular processes and to explore its potential as a drug or biomarker.

Protein Name: Long Intergenic Non-protein Coding RNA 928

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