Target Name: MILR1
NCBI ID: G284021
Other Name(s): MILR1_HUMAN | Allergin-1 | BIR1 | Mast cell immunoglobulin like receptor 1, transcript variant L | C17orf60 | mast cell antigen 32 | probable mast cell antigen 32 homolog | MCA32 | Mast cell immunoglobulin-like receptor 1 | mast cell immunoglobulin like receptor 1 | MCA-32 | Chromosome 17 open reading frame 60 (isoform 3) | Allergin-1 (isoform Allergin-1L) | Allergy inhibitory receptor 1 | Mast cell antigen 32 | allergy inhibitory receptor 1 | Similar to mast cell antigen 32 | B cell immunoglobulin receptor 1 | MILR1 variant L

MILR1: A Protein Involved in Mitochondrial Fusion and Cell Growth

MILR1 (MILR1_HUMAN) is a protein that is expressed in various tissues of the human body, including the brain, heart, kidneys, and pancreas. It is a member of the MILR1 gene family, which encodes for a protein that is involved in the regulation of mitochondrial fusion and fusion-based processes.

One of the unique features of MILR1 is its ability to form a complex with the protein known as Pyruvate Carrier (PyCP), which is a protein that is involved in the transport of pyruvate across the mitochondrial membrane. This complex plays a role in regulating the levels of pyruvate in the mitochondria, which is important for the citric acid cycle and the production of energy.

In addition to its role in regulating pyruvate levels, MILR1 is also involved in the regulation of the expression of other genes. For example, it has been shown to play a role in the regulation of the expression of the gene encoding the protein known as parkin, which is a protein that is involved in the transport of dopamine in the brain.

Another interesting feature of MILR1 is its ability to form a complex with the protein known as TORC, which is a protein that is involved in the regulation of cell growth and metabolism. This complex plays a role in the regulation of the levels of several different proteins, including the protein known as p70S6K, which is involved in the regulation of protein kinase signaling.

MILR1 has also been shown to play a role in the regulation of cellular processes that are important for the development and maintenance of tissues. For example, it has been shown to play a role in the regulation of the formation of new blood vessels, which is important for the growth and development of tissues.

In addition to its role in regulating cellular processes, MILR1 is also involved in the regulation of the structure and function of the mitochondria. For example, it has been shown to play a role in the regulation of the structure and function of the mitochondrial protein known as mitofusin, which is involved in the regulation of mitochondrial fusion and fusion-based processes.

Given its involvement in a wide range of cellular processes, MILR1 is an attractive target for drug development. Research has shown that MILR1 can be targeted with small molecules, such as inhibitors of the protein known as PyCP, which can inhibit the formation of the complex between MILR1 and PyCP. In addition, MILR1 can also be targeted with antibodies that recognize the protein and can be used to block its function in different cellular processes.

In conclusion, MILR1 is a protein that is involved in the regulation of various cellular processes that are important for the development and maintenance of tissues. Its unique ability to form a complex with the protein known as PyCP and the protein known as TORC, as well as its role in the regulation of cellular processes and the structure and function of the mitochondria, make it an attractive target for drug development. Further research is needed to fully understand the role of MILR1 in different cellular processes and to develop effective therapies that can target this protein.

Protein Name: Mast Cell Immunoglobulin Like Receptor 1

Functions: Immunoglobulin-like receptor which plays an inhibitory role in degranulation of mast cells. Negatively regulates IgE-mediated mast cell activation and suppresses the type I immediate hypersensitivity reaction (By similarity)

More Common Targets

MIMT1 | MINAR1 | MINAR2 | MINCR | MINDY1 | MINDY2 | MINDY2-DT | MINDY3 | MINDY4 | Minichromosome maintenance (MCM) 2-7 helicase complex | MINK1 | MINPP1 | MIOS | MIOX | MIP | MIPEP | MIPEPP3 | MIPOL1 | MIR1-1 | MIR1-1HG | MIR1-2 | MIR100 | MIR100HG | MIR101-1 | MIR101-2 | MIR10394 | MIR10396B | MIR10399 | MIR103A1 | MIR103A2 | MIR103B1 | MIR103B2 | MIR105-1 | MIR105-2 | MIR10527 | MIR106A | MIR106B | MIR107 | MIR10A | MIR10B | MIR11181 | MIR11400 | MIR11401 | MIR1178 | MIR1179 | MIR1180 | MIR1181 | MIR1182 | MIR1183 | MIR1184-1 | MIR1184-2 | MIR1184-3 | MIR1185-1 | MIR1185-2 | MIR1193 | MIR1197 | MIR1199 | MIR1200 | MIR1202 | MIR1203 | MIR1204 | MIR1205 | MIR1206 | MIR1207 | MIR1208 | MIR12129 | MIR12135 | MIR12136 | MIR122 | MIR1224 | MIR1225 | MIR1226 | MIR1227 | MIR1228 | MIR1229 | MIR1231 | MIR1233-1 | MIR1233-2 | MIR1234 | MIR1236 | MIR1237 | MIR1238 | MIR124-1 | MIR124-1HG | MIR124-2 | MIR124-2HG | MIR124-3 | MIR1243 | MIR1244-1 | MIR1244-2 | MIR1244-3 | MIR1245A | MIR1245B | MIR1246 | MIR1247 | MIR1248 | MIR1249 | MIR1250 | MIR1251 | MIR1252