ZNF252P: A Potential Cancer Target (G286101)
ZNF252P: A Potential Cancer Target
ZNF252P, also known as Zinc finger protein 252 or pseudogene, is a protein that is expressed in nearly all eukaryotic cells, although its levels vary in different cells. Its full-length code is 611 amino acids and consists of three zinc finger domains, which can bind to DNA and regulate gene expression. In addition, it contains a non-coding RNA region called an intron.
ZNF252P is a member of the zinc finger protein family, which includes a variety of transcription factors, such as NF-Y, TAZ, YY1 and FOXO. These proteins play important roles in signal transduction and gene expression regulation within cells. Zinc finger proteins usually control gene transcription by binding to DNA, thereby affecting biological processes such as cell cycle, DNA damage repair, cell proliferation and apoptosis.
Expression of ZNF252P in various cancers
Many studies have shown that ZNF252P is expressed in a variety of cancers. For example, in lung cancer, the expression level of ZNF252P is higher, while in colorectal cancer and breast cancer, it is lower. In liver cancer and cholangiocarcinoma, the expression level of ZNF252P is also increased. These results indicate that ZNF252P may be a potential tumor target or tumor indicator.
The relationship between ZNF252P and tumors
The expression pattern and functional changes of ZNF252P in tumors may be closely related to the occurrence and development of tumors. Some studies have shown that the expression level of ZNF252P is positively correlated with tumor invasion and metastasis. In liver cancer, the expression level of ZNF252P is significantly related to tumor invasiveness and metastasis, but there is no such relationship in colorectal cancer and breast cancer.
In addition, ZNF252P is also related to tumor self-replication and cell cycle regulation. Studies have shown that ZNF252P plays an important role in the self-replication and cell cycle regulation of tumor cells. It regulates the cycle and growth of tumor cells through interactions with proteins such as CDK4 and CDK6.
Biological functions of ZNF252P
ZNF252P is an important transcription factor that plays an important role in a variety of biological processes. For example, ZNF252P can regulate gene expression, including processes such as cell cycle, cell proliferation, apoptosis, and immune response. It can also regulate DNA damage repair, thereby helping cells fight DNA damage.
In addition, ZNF252P is also closely related to the occurrence and development of tumors. Studies have shown that the expression level of ZNF252P is positively correlated with tumor invasion and metastasis, but there is no such relationship in liver cancer and cholangiocarcinoma. In addition, ZNF252P is also related to tumor self-replication and cell cycle regulation, regulating the cycle and growth of tumor cells through interactions with proteins such as CDK4 and CDK6.
Clinical application of ZNF252P
The expression pattern and functional changes of ZNF252P in tumors may be closely related to the occurrence and development of tumors. Therefore, studying the expression level and function of ZNF252P in tumors may provide new ideas and methods for the diagnosis and treatment of tumors. For example, by detecting the expression level of ZNF252P, the response of tumors to treatment can be evaluated, and it can also be used as a tumor biomarker to predict the survival of tumor patients.
In addition, since ZNF252P is expressed in a variety of cancers, studying ZNF252P may also provide new ideas and methods for general cancer treatment. For example, by studying the mechanism of action of ZNF252P, new drug targets can be explored and new ideas and methods can be provided for personalized treatment of cancer.
ZNF252P is an important transcription factor that plays an important role in a variety of biological processes. Its expression level is positively correlated with tumor invasiveness and metastasis, but there is no such relationship in liver cancer and cholangiocarcinoma.
Protein Name: Zinc Finger Protein 252, Pseudogene
More Common Targets
ZNF252P-AS1 | ZNF253 | ZNF254 | ZNF256 | ZNF257 | ZNF26 | ZNF260 | ZNF263 | ZNF264 | ZNF266 | ZNF267 | ZNF268 | ZNF271P | ZNF273 | ZNF274 | ZNF275 | ZNF276 | ZNF277 | ZNF28 | ZNF280A | ZNF280B | ZNF280C | ZNF280D | ZNF281 | ZNF282 | ZNF283 | ZNF284 | ZNF285 | ZNF285CP | ZNF286A | ZNF286B | ZNF287 | ZNF292 | ZNF295-AS1 | ZNF296 | ZNF3 | ZNF30 | ZNF300 | ZNF300P1 | ZNF302 | ZNF304 | ZNF311 | ZNF316 | ZNF317 | ZNF318 | ZNF319 | ZNF32 | ZNF32-AS1 | ZNF32-AS2 | ZNF32-AS3 | ZNF320 | ZNF321P | ZNF322 | ZNF322P1 | ZNF324 | ZNF324B | ZNF326 | ZNF329 | ZNF330 | ZNF331 | ZNF333 | ZNF334 | ZNF335 | ZNF337 | ZNF33A | ZNF33B | ZNF33BP1 | ZNF34 | ZNF341 | ZNF341-AS1 | ZNF343 | ZNF345 | ZNF346 | ZNF347 | ZNF35 | ZNF350 | ZNF350-AS1 | ZNF354A | ZNF354B | ZNF354C | ZNF355P | ZNF358 | ZNF362 | ZNF365 | ZNF366 | ZNF367 | ZNF37A | ZNF37BP | ZNF382 | ZNF383 | ZNF384 | ZNF385A | ZNF385B | ZNF385C | ZNF385D | ZNF385D-AS1 | ZNF385D-AS2 | ZNF391 | ZNF394 | ZNF395
