ZNF30: A Potential Drug Target and Biomarker (G90075)
ZNF30: A Potential Drug Target and Biomarker
Introduction
Zinc finger proteins (ZFPs) are a family of transmembrane proteins that play a crucial role in various cellular processes. One of the ZFPs, ZNF30, has been identified as a potential drug target and biomarker. In this article, we will explore the biology of ZNF30, its potential as a drug target, and its potential as a biomarker for various diseases.
Biochemistry and Structure
ZNF30 is a 21 kDa protein that contains a N-terminal zinc finger domain, a central 灏?-sheet, and a C-terminal T-loop. The N-terminal zinc finger domain consists of a single zinc finger that consists of two parallel strands of amino acids. The central 灏?-sheet is composed of three parallel strands of amino acids that form a灏?-灏? sandwich. The C-terminal T-loop consists of a single loop of amino acids that is involved in the regulation of zinc finger protein activity.
Function
ZNF30 is involved in various cellular processes, including cell growth, differentiation, and inflammation. It is a key regulator of cell proliferation and has been shown to play a role in the regulation of T-cell development and function. ZNF30 has also been shown to be involved in the regulation of cell migration and the maintenance of stem cell self-renewal. In addition, ZNF30 has been shown to play a role in the regulation of gene expression and has been shown to interact with various transcription factors, including NF-kappa-B and AP-1.
Drug Target
ZNF30 has been identified as a potential drug target due to its unique structure and its involvement in various cellular processes. One of the reasons for its potential as a drug target is its high degree of sensitivity to small molecules, which makes it an attractive target for drug development. In addition, ZNF30 has been shown to play a role in various signaling pathways, including the T-cell receptor signaling pathway, which makes it an attractive target for inhibitors of this pathway.
Biomarker
ZNF30 has also been identified as a potential biomarker for various diseases. For example, ZNF30 has been shown to be involved in the regulation of cancer cell growth and has been shown to play a role in the development of various types of cancer. In addition, ZNF30 has been shown to be involved in the regulation of autoimmune diseases, including rheumatoid arthritis and multiple sclerosis.
Conclusion
In conclusion, ZNF30 is a protein that has the potential to be a drug target and biomarker. Its unique structure and its involvement in various cellular processes make it an attractive target for drug development. Additionally, its potential as a biomarker for various diseases makes it an attractive target for diagnostic studies. Further research is needed to fully understand the biology of ZNF30 and its potential as a drug target and biomarker.
Protein Name: Zinc Finger Protein 30
Functions: May be involved in transcriptional regulation
More Common Targets
ZNF300 | ZNF300P1 | ZNF302 | ZNF304 | ZNF311 | ZNF316 | ZNF317 | ZNF318 | ZNF319 | ZNF32 | ZNF32-AS1 | ZNF32-AS2 | ZNF32-AS3 | ZNF320 | ZNF321P | ZNF322 | ZNF322P1 | ZNF324 | ZNF324B | ZNF326 | ZNF329 | ZNF330 | ZNF331 | ZNF333 | ZNF334 | ZNF335 | ZNF337 | ZNF33A | ZNF33B | ZNF33BP1 | ZNF34 | ZNF341 | ZNF341-AS1 | ZNF343 | ZNF345 | ZNF346 | ZNF347 | ZNF35 | ZNF350 | ZNF350-AS1 | ZNF354A | ZNF354B | ZNF354C | ZNF355P | ZNF358 | ZNF362 | ZNF365 | ZNF366 | ZNF367 | ZNF37A | ZNF37BP | ZNF382 | ZNF383 | ZNF384 | ZNF385A | ZNF385B | ZNF385C | ZNF385D | ZNF385D-AS1 | ZNF385D-AS2 | ZNF391 | ZNF394 | ZNF395 | ZNF396 | ZNF397 | ZNF398 | ZNF402P | ZNF404 | ZNF407 | ZNF407-AS1 | ZNF408 | ZNF41 | ZNF410 | ZNF414 | ZNF415 | ZNF416 | ZNF417 | ZNF418 | ZNF419 | ZNF420 | ZNF423 | ZNF425 | ZNF426 | ZNF428 | ZNF429 | ZNF43 | ZNF430 | ZNF431 | ZNF432 | ZNF433 | ZNF433-AS1 | ZNF436 | ZNF436-AS1 | ZNF438 | ZNF439 | ZNF44 | ZNF440 | ZNF441 | ZNF442 | ZNF443
