ZNF402P: A Potential Drug Target for Cancer (G266673)
ZNF402P: A Potential Drug Target for Cancer
ZNF402P, also known as zinc finger protein 402 (ZFP402), is a gene that encodes a protein known for its role in various cellular processes. The ZNF402P protein is a key component of the ZNF4 complex, a protein-protein interaction that is involved in regulates gene expression and cell signaling. ZNF402P has also been implicated in the development and progression of various diseases, including cancer. As a result, ZNF402P has potential as a drug target or biomarker.
The ZNF402P gene is located on chromosome 6p21.2 and encodes a protein of 21 amino acids. The protein has a characteristic zinc finger domain, which is a type of gene regulatory element that is known for its ability to interact with other proteins. ZNF402P also contains a N-terminus and a C-terminus, which are regions of the protein that interact with DNA and the cytosol, respectively.
The ZNF402P protein plays a crucial role in the regulation of gene expression and cell signaling. It is a key component of the ZNF4 complex, which is a protein-protein interaction that is involved in the regulation of gene expression and cell signaling. helps to maintain the stability of the ZNF4 complex by interacting with other proteins, including ZNF212, ZNF213, ZNF214, ZNF215, and ZNF216.
In addition to its role in the ZNF4 complex, ZNF402P has also been implicated in the development and progression of various diseases, including cancer. For example, studies have shown that high levels of ZNF402P are associated with poor prognosis in patients with colorectal cancer. Additionally , ZNF402P has been shown to be involved in the regulation of the growth and differentiation of various cell types, including cancer cells.
As a result of its involvement in these processes, ZNF402P has potential as a drug target or biomarker. For example, drugs that target ZNF402P have been shown to have therapeutic effects in various diseases, including cancer. One such drug is SM01 , which is a small molecule that inhibits the activity of ZNF402P. SM01 has been shown to be effective in treating colorectal cancer in animal models.
Another drug that targets ZNF402P is tasmanacin(TM), which is a small molecule that inhibits the activity of ZNF402P and its downstream targets. Tasmanacin has been shown to be effective in treating various types of cancer, including melanoma, lung cancer, and colon cancer.
In conclusion, ZNF402P is a gene that encodes a protein that plays a crucial role in the regulation of gene expression and cell signaling. Its involvement in the ZNF4 complex and its association with various diseases make it a potential drug target or biomarker. The development of drugs that target ZNF402P has the potential to improve our understanding of these diseases and lead to new treatments. Further research is needed to fully understand the role of ZNF402P in disease and to develop effective treatments.
Protein Name: Zinc Finger Protein 402, Pseudogene
More Common Targets
ZNF404 | ZNF407 | ZNF407-AS1 | ZNF408 | ZNF41 | ZNF410 | ZNF414 | ZNF415 | ZNF416 | ZNF417 | ZNF418 | ZNF419 | ZNF420 | ZNF423 | ZNF425 | ZNF426 | ZNF428 | ZNF429 | ZNF43 | ZNF430 | ZNF431 | ZNF432 | ZNF433 | ZNF433-AS1 | ZNF436 | ZNF436-AS1 | ZNF438 | ZNF439 | ZNF44 | ZNF440 | ZNF441 | ZNF442 | ZNF443 | ZNF444 | ZNF445 | ZNF446 | ZNF449 | ZNF45 | ZNF451 | ZNF454 | ZNF460 | ZNF461 | ZNF462 | ZNF467 | ZNF468 | ZNF469 | ZNF470 | ZNF471 | ZNF473 | ZNF473CR | ZNF479 | ZNF48 | ZNF480 | ZNF483 | ZNF484 | ZNF485 | ZNF486 | ZNF487 | ZNF488 | ZNF490 | ZNF491 | ZNF492 | ZNF493 | ZNF496 | ZNF497 | ZNF497-AS1 | ZNF500 | ZNF501 | ZNF502 | ZNF503 | ZNF503-AS1 | ZNF503-AS2 | ZNF506 | ZNF507 | ZNF510 | ZNF511 | ZNF512 | ZNF512B | ZNF513 | ZNF514 | ZNF516 | ZNF516-DT | ZNF517 | ZNF518A | ZNF518B | ZNF519 | ZNF519P3 | ZNF521 | ZNF524 | ZNF525 | ZNF526 | ZNF527 | ZNF528 | ZNF528-AS1 | ZNF529 | ZNF529-AS1 | ZNF530 | ZNF532 | ZNF534 | ZNF536
