Target Name: ZNF483
NCBI ID: G158399
Other Name(s): Zinc finger protein 483, transcript variant 1 | ZN483_HUMAN | zinc finger protein 483 | zinc finger protein with KRAB and SCAN domains 16 | Zinc finger protein with KRAB and SCAN domains 16 | ZNF483 variant 1 | zinc finger protein HIT-10 | ZSCAN48 | Zinc finger protein 483 (isoform a) | ZKSCAN16 | Zinc finger protein 483 | Zinc finger protein HIT-10 | KIAA1962

ZNF483: A Potential Drug Target and Biomarker

Zinc finger proteins (ZFPs) are a family of transmembrane proteins that play a crucial role in various cellular processes. ZNF483, also known as Zinc finger protein 483, is a ZNFP that is expressed in various tissues and cell types. It is characterized by the presence of a zinc finger domain and a unique nucleotide-binding oligomerization (NBO) domain. ZNF483 has been implicated in various cellular processes, including cell growth, differentiation, and disease. As a result, it has emerged as a potential drug target and biomarker.

Clinical Importance

ZNF483 has been implicated in the development and progression of various diseases, including cancer, neurodegenerative diseases, and autoimmune diseases. ZNF483 has been shown to play a role in the regulation of cell growth, apoptosis, and angiogenesis. It has also been associated with the development of various diseases, including neurofibromatosis, a genetic disorder that causes tumors, and cancer.

Drug Target Potential

The zinc finger domain is a conserved region that is involved in protein-protein interactions and has been implicated in various cellular processes. ZNF483 has a zinc finger domain that is similar to other zinc finger proteins. This domain is known to interact with various proteins and can modulate their activity. The NBO domain is a unique region that is involved in the regulation of chromatin structure and has been shown to play a role in the regulation of gene expression.

ZNF483 has been shown to interact with various proteins, including its own zinc finger domain and other proteins. It has also been shown to play a role in the regulation of cellular processes, including cell growth, apoptosis, and angiogenesis. As a result, ZNF483 has the potential to be a drug target for various diseases.

Biomarker Potential

ZNF483 has been shown to be involved in the regulation of various cellular processes, including cell growth, apoptosis, and angiogenesis. This suggests that it may be a potential biomarker for various diseases. For example, ZNF483 has been shown to be involved in the regulation of neurofibromatosis, a genetic disorder that causes tumors. It has also been shown to be involved in the regulation of cancer cell growth and angiogenesis.

Conclusion

ZNF483 is a ZNFP that has been implicated in various cellular processes and diseases. Its unique zinc finger domain and NBO domain make it a potential drug target and biomarker. Further research is needed to fully understand the role of ZNF483 in various cellular processes and diseases.

Protein Name: Zinc Finger Protein 483

Functions: May be involved in transcriptional regulation

More Common Targets

ZNF484 | ZNF485 | ZNF486 | ZNF487 | ZNF488 | ZNF490 | ZNF491 | ZNF492 | ZNF493 | ZNF496 | ZNF497 | ZNF497-AS1 | ZNF500 | ZNF501 | ZNF502 | ZNF503 | ZNF503-AS1 | ZNF503-AS2 | ZNF506 | ZNF507 | ZNF510 | ZNF511 | ZNF512 | ZNF512B | ZNF513 | ZNF514 | ZNF516 | ZNF516-DT | ZNF517 | ZNF518A | ZNF518B | ZNF519 | ZNF519P3 | ZNF521 | ZNF524 | ZNF525 | ZNF526 | ZNF527 | ZNF528 | ZNF528-AS1 | ZNF529 | ZNF529-AS1 | ZNF530 | ZNF532 | ZNF534 | ZNF536 | ZNF540 | ZNF541 | ZNF542P | ZNF543 | ZNF544 | ZNF546 | ZNF547 | ZNF548 | ZNF549 | ZNF550 | ZNF551 | ZNF552 | ZNF554 | ZNF555 | ZNF556 | ZNF557 | ZNF558 | ZNF559 | ZNF559-ZNF177 | ZNF560 | ZNF561 | ZNF561-AS1 | ZNF562 | ZNF563 | ZNF564 | ZNF565 | ZNF566 | ZNF566-AS1 | ZNF567 | ZNF568 | ZNF569 | ZNF56P | ZNF57 | ZNF570 | ZNF571 | ZNF571-AS1 | ZNF572 | ZNF573 | ZNF574 | ZNF575 | ZNF576 | ZNF577 | ZNF578 | ZNF579 | ZNF580 | ZNF582 | ZNF582-DT | ZNF583 | ZNF584 | ZNF585A | ZNF585B | ZNF586 | ZNF587 | ZNF587B