Target Name: ZNF526
NCBI ID: G116115
Other Name(s): KIAA1951 | Zinc finger protein 526 | MGC4267 | ZN526_HUMAN | ZNF526 variant 2 | Zinc finger protein 526, transcript variant 2 | zinc finger protein 526 | DENNED | DKFZp762O059

KIAA1951: A Protein Target for Neurodegenerative Diseases

ZNF526 (KIAA1951) is a protein that is expressed in almost all human tissue cells, including neurons, muscle cells, and epithelial cells. Its encoding gene is the ZNF526 gene, which belongs to the chromosome 1p36.1 region. The protein encoded by the ZNF526 gene is a transcription factor, named ZNF526A, also known as KIAA1951.

KIAA1951 plays an important role in cell biology. It plays a key role in a variety of physiological processes, including cell proliferation, differentiation, and apoptosis. KIAA1951 is particularly important in neurons and is essential for neuronal survival and function. In neurons, KIAA1951 is closely related to neuronal survival and apoptosis. When KIAA1951 mutates, it can lead to abnormal death of neurons and the occurrence of neurodegenerative diseases.

Because KIAA1951 plays a key role in a variety of physiological processes, it is considered a potential drug target. Scientists have discovered multiple interaction sites of KIAA1951, which can be used as targets for drug screening. In addition, because KIAA1951 is particularly important in neurons, it is a good potential therapeutic target for neurodegenerative diseases.

In recent years, a lot of drug research on KIAA1951 has been carried out. Scientists have discovered multiple drug targets related to KIAA1951. Among them, PI3K未 receptor is an important molecule that interacts with KIAA1951. Studies have shown that activation of PI3K未 receptors enhances the activity of KIAA1951, leading to neuronal death. Using this discovery, scientists have developed multiple anti-neuron death drugs that can effectively treat neurodegenerative diseases.

In addition to interacting with the PI3K未 receptor, the scientists also discovered a series of important molecules that interact with KIAA1951.

Protein Name: Zinc Finger Protein 526

Functions: May be involved in transcriptional regulation

More Common Targets

ZNF527 | ZNF528 | ZNF528-AS1 | ZNF529 | ZNF529-AS1 | ZNF530 | ZNF532 | ZNF534 | ZNF536 | ZNF540 | ZNF541 | ZNF542P | ZNF543 | ZNF544 | ZNF546 | ZNF547 | ZNF548 | ZNF549 | ZNF550 | ZNF551 | ZNF552 | ZNF554 | ZNF555 | ZNF556 | ZNF557 | ZNF558 | ZNF559 | ZNF559-ZNF177 | ZNF560 | ZNF561 | ZNF561-AS1 | ZNF562 | ZNF563 | ZNF564 | ZNF565 | ZNF566 | ZNF566-AS1 | ZNF567 | ZNF568 | ZNF569 | ZNF56P | ZNF57 | ZNF570 | ZNF571 | ZNF571-AS1 | ZNF572 | ZNF573 | ZNF574 | ZNF575 | ZNF576 | ZNF577 | ZNF578 | ZNF579 | ZNF580 | ZNF582 | ZNF582-DT | ZNF583 | ZNF584 | ZNF585A | ZNF585B | ZNF586 | ZNF587 | ZNF587B | ZNF589 | ZNF592 | ZNF593 | ZNF594 | ZNF594-DT | ZNF595 | ZNF596 | ZNF597 | ZNF598 | ZNF599 | ZNF600 | ZNF603P | ZNF605 | ZNF606 | ZNF607 | ZNF608 | ZNF609 | ZNF610 | ZNF611 | ZNF613 | ZNF614 | ZNF615 | ZNF616 | ZNF618 | ZNF619 | ZNF620 | ZNF621 | ZNF622 | ZNF623 | ZNF624 | ZNF625 | ZNF625-ZNF20 | ZNF626 | ZNF627 | ZNF628 | ZNF629 | ZNF630