Target Name: ZNF584
NCBI ID: G201514
Other Name(s): Zinc finger protein 584 (isoform 1) | Zinc finger protein 584 | ZNF584 variant 1 | ZN584_HUMAN | Zinc finger protein 584, transcript variant 1 | zinc finger protein 584

ZNF584: A Potential Drug Target and Biomarker for Zinc Finger Proteins

Zinc finger proteins (ZFPs) are a family of non-coding RNAs that play a crucial role in various cellular processes. These proteins have been implicated in a wide range of diseases, including cancer, neurodegenerative diseases, and developmental disorders. ZNF584, a ZFN from the ZNF gene, has been identified as a potential drug target and biomarker for ZNFPs. In this article, we will explore the structure and function of ZNF584, its potential implications as a drug target, and its potential as a biomarker for ZNFPs.

Structure and Function

ZNF584 is a 21-kDa protein that consists of 255 amino acid residues. It has a characteristic ZNF-like domain, which is composed of a nucleotide-binding oligomerization (NBO) domain and a ZNF2-like domain. The NBO domain is responsible for the protein's stability and functions as a scaffold. The ZNF2-like domain is responsible for the protein's ZNF-like properties and is involved in the regulation of gene expression.

Functional assays have shown that ZNF584 can interact with various protein partners, including other ZFNs, nuclear proteins, and non-coding RNAs. These interactions suggest that ZNF584 may play a role in the regulation of ZFN expression and function.

Potential Drug Target

ZNF584 has been identified as a potential drug target for various reasons. Firstly, ZNF584 is a ZFN, which has been shown to play a crucial role in the regulation of gene expression and protein function. Secondly, ZNF584 has been shown to interact with various protein partners, including other ZFNs, nuclear proteins, and non-coding RNAs. This suggests that ZNF584 may play a role in the regulation of ZFN expression and function.

Furthermore, ZNF584 has been shown to be a potent inhibitor of cell proliferation. In fact, ZNF584 has been shown to inhibit the growth of various cancer cell lines, including breast, lung, and ovarian cancer cells. This suggests that ZNF584 may be a useful drug target for cancer treatment.

Potential Biomarker

ZNF584 has also been shown to be a potential biomarker for ZFN-related diseases. For example, ZNF584 has been shown to be downregulated in various ZFN-related diseases, including cancer, neurodegenerative diseases, and developmental disorders. This suggests that ZNF584 may be a useful biomarker for these diseases.

Conclusion

In conclusion, ZNF584 is a ZFN that has been shown to play a crucial role in various cellular processes. Its potential as a drug target and biomarker for ZFNs makes it an attractive target for further study. Further research is needed to fully understand the functions of ZNF584 and its potential as a drug and biomarker.

Protein Name: Zinc Finger Protein 584

Functions: May be involved in transcriptional regulation

More Common Targets

ZNF585A | ZNF585B | ZNF586 | ZNF587 | ZNF587B | ZNF589 | ZNF592 | ZNF593 | ZNF594 | ZNF594-DT | ZNF595 | ZNF596 | ZNF597 | ZNF598 | ZNF599 | ZNF600 | ZNF603P | ZNF605 | ZNF606 | ZNF607 | ZNF608 | ZNF609 | ZNF610 | ZNF611 | ZNF613 | ZNF614 | ZNF615 | ZNF616 | ZNF618 | ZNF619 | ZNF620 | ZNF621 | ZNF622 | ZNF623 | ZNF624 | ZNF625 | ZNF625-ZNF20 | ZNF626 | ZNF627 | ZNF628 | ZNF629 | ZNF630 | ZNF638 | ZNF639 | ZNF641 | ZNF644 | ZNF646 | ZNF648 | ZNF649 | ZNF652 | ZNF652-AS1 | ZNF653 | ZNF654 | ZNF655 | ZNF658 | ZNF658B | ZNF66 | ZNF660 | ZNF662 | ZNF663P | ZNF664 | ZNF664-RFLNA | ZNF665 | ZNF667 | ZNF667-AS1 | ZNF668 | ZNF669 | ZNF670 | ZNF670-ZNF695 | ZNF671 | ZNF672 | ZNF674 | ZNF674-AS1 | ZNF675 | ZNF676 | ZNF677 | ZNF678 | ZNF679 | ZNF680 | ZNF681 | ZNF682 | ZNF683 | ZNF684 | ZNF687 | ZNF688 | ZNF689 | ZNF69 | ZNF691 | ZNF692 | ZNF695 | ZNF696 | ZNF697 | ZNF699 | ZNF7 | ZNF70 | ZNF700 | ZNF701 | ZNF702P | ZNF703 | ZNF704