Target Name: ZNF674
NCBI ID: G641339
Other Name(s): Zinc finger protein 674 (isoform 1) | Zinc finger protein 674, transcript variant 1 | zinc finger family member 674 | Zinc finger protein 674 | ZN674_HUMAN | ZNF673B | Zinc finger protein 674, transcript variant 2 | zinc finger protein 674 | ZNF674 variant 1 | ZNF674 variant 2 | MRX92

ZNF674: A Potential Drug Target and Biomarker for Chronic Pain

Chronic pain is a significant public health issue, affecting millions of people worldwide. The chronic pain experience can lead to significant morbidity and mortality, as well as decreased quality of life. The ZNF674 gene, which encodes zinc finger protein 674 (isoform 1), has been identified as a potential drug target and biomarker for chronic pain. In this article, we will discuss the ZNF674 gene, its function, and its potential as a drug target and biomarker for chronic pain.

ZNF674 gene and protein

The ZNF674 gene is located on chromosome 11q22 and encodes a protein known as zinc finger protein 674 (isoform 1). The protein is a member of the zinc finger gene family, which is characterized by the presence of a zinc finger domain in its protein sequence. The zinc finger domain is a conserved region that is characterized by the presence of a nucleotide-binding oligomerization domain (NBO domain), a hypervariable region (HVR), and a C-terminal domain.

The ZNF674 protein is a 21-kDa protein that contains 109 amino acid residues. The protein has a characteristic N-terminal hypervariable region that is involved in its stability and functions as a protein. The ZNF674 protein is also known for its ability to form a protein-protein interaction (PPI) complex with other proteins, including the neurotransmitter GABA. This interaction between the ZNF674 protein and GABA plays a crucial role in its function in modulating pain signaling.

ZNF674 as a drug target

The ZNF674 protein has been identified as a potential drug target for chronic pain due to its involvement in pain signaling. The ZNF674 protein is involved in the modulation of pain signaling by interacting with GABA, which is a neurotransmitter that has inverse effects on pain signaling. GABA is known for its ability to inhibit the activity of ion channels, which are involved in pain signaling.

The ZNF674 protein is also involved in the modulation of pain signaling by interacting with other proteins, including the neurotransmitter opioid. The ZNF674 protein has been shown to interact with the opioid receptor, which is involved in pain signaling. This interaction between the ZNF674 protein and the opioid receptor suggests that the ZNF674 protein may be a useful target for the treatment of chronic pain.

ZNF674 as a biomarker

The ZNF674 protein may also be used as a biomarker for chronic pain. The ZNF674 protein is expressed in a variety of tissues, including brain, heart, and muscle. Therefore, its expression level can be used as a biomarker for the diagnosis and monitoring of chronic pain.

The ZNF674 protein has been shown to be expressed in the brain and has been linked to the development of chronic pain. Studies have shown that the ZNF674 protein is involved in the modulation of pain signaling in the brain and may play a role in the development of chronic pain. Therefore, the ZNF674 protein may be a useful biomarker for the diagnosis and monitoring of chronic pain.

Conclusion

In conclusion, the ZNF674 gene has been identified as a potential drug target and biomarker for chronic pain. The ZNF674 protein is involved in the modulation of pain signaling by interacting with GABA and other proteins, including the opioid receptor. Its expression level can be used as a biomarker for the diagnosis and monitoring of chronic pain. Further research is needed to determine the effectiveness of the ZNF674 protein as a drug target and biomarker for chronic

Protein Name: Zinc Finger Protein 674

Functions: May be involved in transcriptional regulation

More Common Targets

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