Stem Cell Regulation and Disease Association (G342132)
Stem Cell Regulation and Disease Association
ZNF774 (MGC75360) is a protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. It is a key regulator of stem cell proliferation and has been linked to a number of diseases, including neurodegenerative disorders, cancer, and autoimmune diseases.
One of the defining features of ZNF774 is its role in regulating the stem cell pool. Stem cells are a type of cell that have the ability to give rise to all of the different cell types of the body, and they play a critical role in maintaining tissue repair and regeneration. ZNF774 is essential for the proper functioning of stem cells, and research has suggested that it may be a potential drug target or biomarker for a number of diseases.
ZNF774 has been shown to play a role in a number of neurodegenerative disorders, including Alzheimer's disease, Parkinson's disease, and Huntington's disease. These disorders are characterized by the progressive loss of brain cells and the damage that results. ZNF774 has been shown to be expressed in the brains of individuals with these disorders, and it has been linked to the misfolding of a protein called TDP-4, which is a key regulator of stem cells.
In addition to its role in neurodegenerative disorders, ZNF774 has also been linked to the development and progression of cancer. Many studies have suggested that ZNF774 plays a role in the regulation of cell proliferation, and that it may be a potential drug target for cancer. For example, research has shown that ZNF774 is expressed in a variety of cancer types, including breast, lung, and ovarian cancer.
ZNF774 has also been shown to be involved in autoimmune diseases, such as rheumatoid arthritis and lupus. These disorders are characterized by the immune system attacking the body's own tissues, and they can cause a range of symptoms and disabilities. ZNF774 has been shown to be involved in the regulation of immune cells, and research has suggested that it may be a potential drug target or biomarker for these disorders.
Despite its potential as a drug target or biomarker, ZNF774 is still a relatively little-studied protein. There are only a few studies that have explored its role in neural stem cells and the effects of drugs on its expression. Further research is needed to fully understand the role of ZNF774 in these processes and to determine its potential as a drug.
In conclusion, ZNF774 is a protein that has been shown to play a critical role in the regulation of stem cell proliferation and the development and progression of a variety of diseases, including neurodegenerative disorders, cancer, and autoimmune diseases. Further research is needed to fully understand its role and potential as a drug target or biomarker.
Protein Name: Zinc Finger Protein 774
Functions: May be involved in transcriptional regulation
More Common Targets
ZNF775 | ZNF776 | ZNF777 | ZNF778 | ZNF780A | ZNF780B | ZNF781 | ZNF782 | ZNF783 | ZNF784 | ZNF785 | ZNF786 | ZNF787 | ZNF788P | ZNF789 | ZNF79 | ZNF790 | ZNF790-AS1 | ZNF791 | ZNF792 | ZNF793 | ZNF799 | ZNF8 | ZNF8-ERVK3-1 | ZNF80 | ZNF800 | ZNF804A | ZNF804B | ZNF805 | ZNF807P | ZNF808 | ZNF81 | ZNF812P | ZNF813 | ZNF814 | ZNF815P | ZNF816 | ZNF816-ZNF321P | ZNF818P | ZNF821 | ZNF823 | ZNF826P | ZNF827 | ZNF829 | ZNF83 | ZNF830 | ZNF831 | ZNF833P | ZNF835 | ZNF836 | ZNF837 | ZNF839 | ZNF839P1 | ZNF84 | ZNF840P | ZNF841 | ZNF843 | ZNF844 | ZNF845 | ZNF846 | ZNF85 | ZNF850 | ZNF852 | ZNF853 | ZNF860 | ZNF862 | ZNF865 | ZNF875 | ZNF876P | ZNF878 | ZNF879 | ZNF880 | ZNF883 | ZNF887P | ZNF888 | ZNF890P | ZNF891 | ZNF90 | ZNF91 | ZNF92 | ZNF93 | ZNF962P | ZNF98 | ZNF99 | ZNFX1 | ZNG1A | ZNG1B | ZNG1C | ZNG1E | ZNG1F | ZNHIT1 | ZNHIT2 | ZNHIT3 | ZNHIT6 | ZNRD2 | ZNRD2-DT | ZNRF1 | ZNRF2 | ZNRF2P1 | ZNRF3
