ZNF90 Gene as Potential Drug Target, Biomarker for Neurological Disorders

Target Name: ZNF90

NCBI ID: G7643

ZNF90 Gene as Potential Drug Target, Biomarker for Neurological Disorders

ZNF90 (ZNF90_HUMAN), a gene that encodes for a protein known as ZNF90, is a key regulator of neural development and function. The ZNF90 gene has been identified as a potential drug target and biomarker for various neurological and psychiatric disorders, including schizophrenia, depression, and anxiety.

The ZNF90 protein is a transcription factor that plays a crucial role in the regulation of gene expression. It is expressed in various tissues and cell types, including neurons, and is involved in the development, organization, and function of neural circuits. The ZNF90 protein has been shown to be involved in the regulation of various neural circuits, including the development and plasticity of the cerebral cortical cortex, the formation of memory and learning, and the regulation of movement and behavior.

ZNF90 has been shown to play a role in the development and progression of several neurological and psychiatric disorders, including schizophrenia, depression, and anxiety. Studies have shown that individuals with schizophrenia, depression, and anxiety have lower levels of ZNF90 protein in their brains compared to healthy individuals. Additionally, individuals with schizophrenia have lower levels of ZNF90 mRNA in their brains compared to healthy individuals.

The ZNF90 protein is also a potential biomarker for these disorders. Studies have shown that ZNF90 mRNA levels can be increased in individuals with schizophrenia, depression, and anxiety, and that these individuals have lower levels of ZNF90 protein in their brains compared to healthy individuals. Additionally, individuals with schizophrenia have lower levels of ZNF90 mRNA in their brains compared to healthy individuals, which suggests that ZNF90 may be a useful biomarker for this disorder.

In addition to its potential role as a drug target and biomarker, ZNF90 is also of interest as a potential therapeutic approach. Studies have shown that inhibiting the activity of ZNF90 can be effective in treating symptoms of schizophrenia, depression, and anxiety. Additionally, drugs that increase the level of ZNF90 protein have been shown to be effective in treating these disorders.

Overall, ZNF90 is a gene that has significant implications for the development and treatment of neurological and psychiatric disorders. Further research is needed to fully understand its role in these disorders and to develop effective treatments.

Protein Name: Zinc Finger Protein 90

Functions: May be involved in transcriptional regulation

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