ZNF8: The Zinc Finger Protein 8 (Clone HF.18) (G7554)

ZNF8: The Zinc Finger Protein 8 (Clone HF.18)

Zinc finger proteins (ZFPs) are a family of non-coding RNAs that play a crucial role in various cellular processes. One of the most well-studied ZFPs is ZNF8, also known as clone HF.18. ZNF8 is a 21-kDa protein that is expressed in most tissues of the body. It is characterized by the presence of a zinc finger domain and a unique N-terminal region that contains a conserved core structure. ZNF8 is involved in various cellular processes, including cell growth, differentiation, and inflammation.

The zinc finger domain is a structural feature that is characterized by the presence of a nucleotide-binding zinc finger that is responsible for the protein's unique structure and function. The zinc finger domain is responsible for the formation of a distinct protein structure that is composed of a conserved core region, a N-terminal region, and a C-terminal region. The N-terminal region is rich in various functional domains, including a nucleotide-binding domain, a scaffold domain, and a motif that is involved in protein-protein interactions.

ZNF8 is involved in various cellular processes, including cell growth, differentiation, and inflammation. It is a key regulator of cell growth and has been shown to play a role in the regulation of cell cycle progression. ZNF8 is also involved in the regulation of cell differentiation and has been shown to play a role in the regulation of neural stem cell proliferation.

In addition to its role in cell biology, ZNF8 has also been shown to be involved in the regulation of inflammation. It is a key regulator of the immune response and has been shown to play a role in the regulation of inflammation. ZNF8 has been shown to be involved in the regulation of T cell development and has been shown to play a role in the regulation of inflammation in the gut.

ZNF8 has also been shown to be a potential drug target. Its unique structure and function, as well as its involvement in various cellular processes, make it an attractive target for drug development. Several studies have shown that ZNF8 can be targeted by small molecules and have identified potential drug candidates. These drugs can then be tested for their ability to interact with ZNF8 and modulate its function.

In conclusion, ZNF8 is a conserved protein that is involved in various cellular processes. Its unique structure and function, as well as its involvement in various processes, make it an attractive target for drug development. Further research is needed to fully understand the role of ZNF8 in cell biology and its potential as a drug target.

Protein Name: Zinc Finger Protein 8

Functions: Transcriptional repressor. May modulate BMP and TGF-beta signal transduction, through its interaction with SMAD proteins

More Common Targets

ZNF8-ERVK3-1 | ZNF80 | ZNF800 | ZNF804A | ZNF804B | ZNF805 | ZNF807P | ZNF808 | ZNF81 | ZNF812P | ZNF813 | ZNF814 | ZNF815P | ZNF816 | ZNF816-ZNF321P | ZNF818P | ZNF821 | ZNF823 | ZNF826P | ZNF827 | ZNF829 | ZNF83 | ZNF830 | ZNF831 | ZNF833P | ZNF835 | ZNF836 | ZNF837 | ZNF839 | ZNF839P1 | ZNF84 | ZNF840P | ZNF841 | ZNF843 | ZNF844 | ZNF845 | ZNF846 | ZNF85 | ZNF850 | ZNF852 | ZNF853 | ZNF860 | ZNF862 | ZNF865 | ZNF875 | ZNF876P | ZNF878 | ZNF879 | ZNF880 | ZNF883 | ZNF887P | ZNF888 | ZNF890P | ZNF891 | ZNF90 | ZNF91 | ZNF92 | ZNF93 | ZNF962P | ZNF98 | ZNF99 | ZNFX1 | ZNG1A | ZNG1B | ZNG1C | ZNG1E | ZNG1F | ZNHIT1 | ZNHIT2 | ZNHIT3 | ZNHIT6 | ZNRD2 | ZNRD2-DT | ZNRF1 | ZNRF2 | ZNRF2P1 | ZNRF3 | ZNRF3-AS1 | ZNRF4 | ZP1 | ZP2 | ZP3 | ZP4 | ZPBP | ZPBP2 | ZPLD1 | ZPLD2P | ZPR1 | ZRANB1 | ZRANB2 | ZRANB2-AS1 | ZRANB2-DT | ZRANB3 | ZRS | ZRSR2 | ZRSR2P1 | ZSCAN1 | ZSCAN10 | ZSCAN12 | ZSCAN12P1