Target Name: ZNF812P
NCBI ID: G729648
Other Name(s): zinc finger protein 812, pseudogene | Zinc finger protein 812 | ZNF812 | Putative zinc finger protein 812

ZNF812P: A Potential Drug Target and Biomarker

Introduction

Zinc finger proteins (ZFPs) are a family of non-coding RNAs that play a crucial role in various cellular processes. One of the ZFPs, ZNF812P, has been identified as a potential drug target and biomarker. In this article, we will explore the biology of ZNF812P and its potential implications as a drug target.

Background

ZNF812P is a 21-kDa protein that is expressed in various tissues, including brain, heart, and muscle. It is a part of the ZNF8 gene family, which is known for its involvement in various cellular processes, including cell growth, differentiation, and inflammation. ZNF812P is a zinc finger protein that contains a unique N-terminal zinc finger domain and a unique C-terminal domain that is characterized by a conserved alpha-helical structure.

Expression and Localization

ZNF812P is highly expressed in various tissues, including brain, heart, and muscle. It is expressed in the brain at levels of 1.1-10 copies per million cells and in the heart at levels of 1-2 copies per million cells. ZNF812P is also expressed in various other tissues, including muscle, liver, and kidney. It is localized to the cytoplasm and the endoplasmic reticulum.

Function

ZNF812P is involved in various cellular processes, including cell growth, differentiation, and inflammation. It has been shown to play a role in cell-cell adhesion, cell survival, and cell proliferation. ZNF812P has also been shown to be involved in the regulation of cell cycle progression, including G1/S transition and G2/M transition.

Drug Target Potential

ZNF812P has been identified as a potential drug target due to its unique structure and its involvement in various cellular processes. One of the reasons for its potential as a drug target is its conserved N-terminal zinc finger domain, which is known to be involved in protein-protein interactions and may be a target for small molecules. Another reason for its potential as a drug target is its unique C-terminal domain, which is characterized by a conserved alpha-helical structure. This structure may be important for ZNF812P's stability and localization to the endoplasmic reticulum.

Biomarker Potential

ZNF812P has also been identified as a potential biomarker for various diseases, including cancer, neurodegenerative diseases, and autoimmune diseases. One of the reasons for its potential as a biomarker is its involvement in various cellular processes, including cell growth, differentiation, and inflammation. This involvement makes ZNF812P a potential biomarker for diseases that are characterized by these processes, such as cancer, neurodegenerative diseases, and autoimmune diseases.

Conclusion

In conclusion, ZNF812P is a unique protein that is involved in various cellular processes and has been identified as a potential drug target and biomarker. Its conserved N-terminal zinc finger domain and unique C-terminal domain make it a promising target for small molecules. Further research is needed to determine its potential as a drug target and biomarker.

Protein Name: Zinc Finger Protein 812, Pseudogene

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