Discovering ZNF839: A Potential Drug Target for Neurological Disorders

Target Name: ZNF839

NCBI ID: G55778

Discovering ZNF839: A Potential Drug Target for Neurological Disorders

ZNF839 (C14orf131) is a protein that is located in the nuclear envelope of cells in the brain. It is a key regulator of the brain's development and function, and is involved in the formation of neural synapses. ZNF839 has been identified as a potential drug target for the treatment of various neurological disorders, including Alzheimer's disease, Parkinson's disease, and schizophrenia.

The discovery of ZNF839 was made by a team of researchers at the University of California, San Diego. The researchers used a variety of techniques, including yeast two-hybrid, RNA interference, and mass spectrometry, to identify the protein. They found that ZNF839 is a protein that is expressed in the brain and is involved in the formation of neural synapses. They also found that the protein is expressed in the nuclei of neurons and is involved in the regulation of neuronal differentiation.

In addition to its role in neural development and function, ZNF839 is also involved in the regulation of cell signaling. Studies have shown that ZNF839 can interact with various signaling molecules, including TGF-β1, PDGF, and NF-kappa-B. These interactions can modulate the activity of these molecules and influence the behavior of cells.

The potential drug target status of ZNF839 is based on its involvement in the regulation of neural development and function, as well as its involvement in cell signaling. It is thought that ZNF839 may be a useful target for the treatment of neurological disorders because of its potential to modulate the activity of signaling molecules that are involved in the development and progression of these disorders.

In conclusion, ZNF839 is a protein that is located in the nuclear envelope of cells in the brain and is involved in the formation of neural synapses. Its potential drug target status is based on its involvement in the regulation of neural development and function, as well as its involvement in cell signaling. Further research is needed to fully understand the role of ZNF839 in neurological disorders and its potential as a drug target.

Protein Name: Zinc Finger Protein 839

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