ZNF74: A Potential Drug Target for Many Diseases (G7625)
ZNF74: A Potential Drug Target for Many Diseases
ZNF74 (Zinc Finger Nucleosome 74) is a protein that is expressed in almost all human tissues and is known for its role in the maintenance of cellular genomic stability. ZNF74 is a key component of the nucleosome, which is the basic unit of DNA in the nucleus of a cell. The nucleosome is composed of a protein called histone and a small RNA molecule called histone mRNA. ZNF74 helps to physically secure the histone to the DNA by interacting with the histone's N-terminus.
Recent studies have identified ZNF74 as a potential drug target for a variety of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. The reason for this is that ZNF74 is involved in the regulation of cellular processes that are important for the development and progression of these diseases.
One of the key mechanisms by which ZNF74 is involved in the regulation of cellular processes is its role in the maintenance of genomic stability. Genomic instability is a hallmark feature of cancer, and it is thought to contribute to the development and progression of many diseases. ZNF74 helps to maintain the stability of the genomic material by ensuring that the histone-DNA complex is physically secure.
In addition to its role in genomic stability, ZNF74 is also involved in the regulation of cellular signaling pathways. Specifically, ZNF74 has been shown to be involved in the regulation of the Wnt signaling pathway, a pathway that is important for the development and maintenance of tissues and organs.
The Wnt signaling pathway is a critical regulator of development and tissue growth, and it is thought to play a key role in the development of many diseases, including cancer. ZNF74 has been shown to be involved in the regulation of the Wnt signaling pathway by interacting with the protein FGF1, which is a key regulator of the pathway.
FGF1 is a transmembrane protein that is involved in the regulation of cell signaling pathways, including the Wnt signaling pathway. It is thought to play a key role in the development and maintenance of tissues and organs, and it is a potential drug target for many diseases. ZNF74 has been shown to be involved in the regulation of FGF1 activity by interacting with its N-terminus.
In conclusion, ZNF74 is a protein that is involved in the regulation of cellular processes that are important for the development and progression of many diseases. Its role in the maintenance of genomic stability and its involvement in the regulation of cellular signaling pathways make it a potential drug target for a variety of diseases. Further research is needed to fully understand the role of ZNF74 in the development and progression of these diseases.
Protein Name: Zinc Finger Protein 74
Functions: May play a role in RNA metabolism
More Common Targets
ZNF740 | ZNF746 | ZNF747 | ZNF749 | ZNF750 | ZNF75A | ZNF75CP | ZNF75D | ZNF76 | ZNF761 | ZNF763 | ZNF764 | ZNF765 | ZNF766 | ZNF767P | ZNF768 | ZNF77 | ZNF770 | ZNF771 | ZNF772 | ZNF773 | ZNF774 | ZNF775 | ZNF776 | ZNF777 | ZNF778 | ZNF780A | ZNF780B | ZNF781 | ZNF782 | ZNF783 | ZNF784 | ZNF785 | ZNF786 | ZNF787 | ZNF788P | ZNF789 | ZNF79 | ZNF790 | ZNF790-AS1 | ZNF791 | ZNF792 | ZNF793 | ZNF799 | ZNF8 | ZNF8-ERVK3-1 | ZNF80 | ZNF800 | ZNF804A | ZNF804B | ZNF805 | ZNF807P | ZNF808 | ZNF81 | ZNF812P | ZNF813 | ZNF814 | ZNF815P | ZNF816 | ZNF816-ZNF321P | ZNF818P | ZNF821 | ZNF823 | ZNF826P | ZNF827 | ZNF829 | ZNF83 | ZNF830 | ZNF831 | ZNF833P | ZNF835 | ZNF836 | ZNF837 | ZNF839 | ZNF839P1 | ZNF84 | ZNF840P | ZNF841 | ZNF843 | ZNF844 | ZNF845 | ZNF846 | ZNF85 | ZNF850 | ZNF852 | ZNF853 | ZNF860 | ZNF862 | ZNF865 | ZNF875 | ZNF876P | ZNF878 | ZNF879 | ZNF880 | ZNF883 | ZNF887P | ZNF888 | ZNF890P | ZNF891 | ZNF90
