Target Name: ZNF703
NCBI ID: G80139
Other Name(s): FLJ14299 | zinc finger elbow-related proline domain protein 1 | Zinc finger elbow-related proline domain protein 1 | ZNF503L | zinc finger protein 703 | Zinc finger protein 703 | ZEPPO1 | ZN703_HUMAN | ZPO1 | NLZ1

ZNF703: A Potential Drug Target for Cellular Processes and Tissue Regeneration

ZNF703 (FLJ14299) is a protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. It is a member of the ZNF family of proteins, which are known for their role in regulating gene expression and cell growth . ZNF703 has been identified as a potential drug target and has been shown to play a role in a variety of biological processes, including cell proliferation, differentiation, and survival.

The ZNF family of proteins was identified in the 1990s based on the discovery of a family of genes that were expressed in neural tube development and were involved in the regulation of neuronal stem cell proliferation. The ZNF genes encode for a variety of proteins that have been shown to play important roles in regulating gene expression and cell growth. Many of these proteins are involved in the regulation of cell adhesion, cell signaling, and cellular decision-making, and are thought to be involved in the development and maintenance of tissues and organs.

ZNF703 is a 21-kDa protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. It is a member of the ZNF family of proteins and is characterized by the presence of several unique amino acid residues, including a juxtamolecular F-actinylation and a conserved N-terminal hypervariable region (HVR). The F-actinylation is a type of modification that has been shown to play a role in the regulation of protein stability and function, and the N-terminal HVR is a region of the protein that is involved in its stability and translation.

ZNF703 has been shown to play a role in a variety of biological processes, including cell proliferation, differentiation, and survival. For example, studies have shown that overexpression of ZNF703 can lead to the growth of cancer cells and the development of invasive tumors. In In addition, ZNF703 has been shown to play a role in the regulation of neuronal stem cell proliferation and the development of neural tube defects.

In addition to its role in cell biology, ZNF703 has also been identified as a potential drug target. The high level of expression of ZNF703 in various tissues and the involvement in a variety of cellular processes make it an attractive target for drug development. Furthermore, the F-actinylation and N-terminal HVR properties of ZNF703 make it a likely candidate for inhibition by small molecules or antibodies.

In conclusion, ZNF703 is a protein that is expressed in various tissues of the body and is a member of the ZNF family of proteins. It has been shown to play a role in a variety of cellular processes, including cell proliferation, differentiation, and survival . In addition, ZNF703 has been identified as a potential drug target due to its high level of expression and the unique F-actinylation and N-terminal HVR properties of the protein. Further research is needed to understand the full role of ZNF703 in cell biology and to explore its potential as a drug target.

Protein Name: Zinc Finger Protein 703

Functions: Transcriptional corepressor which does not bind directly to DNA and may regulate transcription through recruitment of histone deacetylases to gene promoters. Regulates cell adhesion, migration and proliferation. May be required for segmental gene expression during hindbrain development

More Common Targets

ZNF704 | ZNF705A | ZNF705B | ZNF705CP | ZNF705EP | ZNF705G | ZNF706 | ZNF707 | ZNF708 | ZNF709 | ZNF71 | ZNF710 | ZNF711 | ZNF713 | ZNF714 | ZNF716 | ZNF717 | ZNF718 | ZNF721 | ZNF723 | ZNF724 | ZNF726 | ZNF727 | ZNF728 | ZNF729 | ZNF730 | ZNF732 | ZNF734P | ZNF735 | ZNF736 | ZNF737 | ZNF738 | ZNF74 | ZNF740 | ZNF746 | ZNF747 | ZNF749 | ZNF750 | ZNF75A | ZNF75CP | ZNF75D | ZNF76 | ZNF761 | ZNF763 | ZNF764 | ZNF765 | ZNF766 | ZNF767P | ZNF768 | ZNF77 | ZNF770 | ZNF771 | ZNF772 | ZNF773 | ZNF774 | ZNF775 | ZNF776 | ZNF777 | ZNF778 | ZNF780A | ZNF780B | ZNF781 | ZNF782 | ZNF783 | ZNF784 | ZNF785 | ZNF786 | ZNF787 | ZNF788P | ZNF789 | ZNF79 | ZNF790 | ZNF790-AS1 | ZNF791 | ZNF792 | ZNF793 | ZNF799 | ZNF8 | ZNF8-ERVK3-1 | ZNF80 | ZNF800 | ZNF804A | ZNF804B | ZNF805 | ZNF807P | ZNF808 | ZNF81 | ZNF812P | ZNF813 | ZNF814 | ZNF815P | ZNF816 | ZNF816-ZNF321P | ZNF818P | ZNF821 | ZNF823 | ZNF826P | ZNF827 | ZNF829 | ZNF83