ZNF574: A Non-Code RNA Molecule Implicated in Cancer and Stem Cell Proliferation

ZNF574: A Non-Code RNA Molecule Implicated in Cancer and Stem Cell Proliferation

ZNF574 (FP972), a protein encoded by the gene ZNF574 (Zinc Finger Nucleotide Substrate 574), is a non-coding RNA molecule that plays a critical role in various cellular processes. ZNF574 is a key regulator of stem cell proliferation and has been linked to the development and progression of various diseases, including cancer.

The ZNF574 protein is composed of a unique nucleotide sequence that includes a zinc finger domain and a short interspacer DNA sequence. The zinc finger domain is a well-known structural motif that is characterized by the presence of a central zinc atom and four amino acids that are highly conserved in various species, including humans. The short interspacer DNA sequence is a non-coding sequence that is located upstream of the zinc finger domain and has been implicated in various functions, including regulation of gene expression and DNA replication.

ZNF574 is highly expressed in various tissues and has been implicated in the development and progression of various diseases, including cancer. For example, studies have shown that high levels of ZNF574 are associated with poor prognosis in individuals with pancreatic ductal adenocarcinoma, a type of cancer that arises from the ducts that carry bile from the pancreas to the small intestine. Additionally, ZNF574 has been shown to be highly expressed in various types of cancer, including breast, ovarian, and colorectal cancer.

In addition to its role in cancer, ZNF574 has also been implicated in the regulation of stem cell proliferation. Stem cells are a diverse group of cells that have the ability to self-renew and differentiate into various cell types, and the regulation of stem cell proliferation is critical for the development and maintenance of tissues and organs. ZNF574 has been shown to play a role in regulating the growth and differentiation of stem cells, and studies have shown that it is involved in the regulation of stem cell proliferation and the maintenance of stem cell stemness.

ZNF574 has also been implicated in the regulation of tissue homeostasis. Tissue homeostasis refers to the ability of tissues to maintain a stable environment that is necessary for proper cellular function and survival. ZNF574 has been shown to play a role in regulating the balance between stem cell proliferation and tissue homeostasis, and its expression has been implicated in the regulation of various tissues, including the skin, hair, and nails.

In conclusion, ZNF574 is a non-coding RNA molecule that is highly expressed in various tissues and has been implicated in the development and progression of various diseases, including cancer. Its role in stem cell proliferation and tissue homeostasis suggests that it may be a promising drug target or biomarker for the treatment of these diseases. Further research is needed to fully understand the mechanisms of ZNF574 and its potential as a drug or biomarker.

Protein Name: Zinc Finger Protein 574

Functions: May be involved in transcriptional regulation

More Common Targets

ZNF575 | ZNF576 | ZNF577 | ZNF578 | ZNF579 | ZNF580 | ZNF582 | ZNF582-DT | ZNF583 | ZNF584 | ZNF585A | ZNF585B | ZNF586 | ZNF587 | ZNF587B | ZNF589 | ZNF592 | ZNF593 | ZNF594 | ZNF594-DT | ZNF595 | ZNF596 | ZNF597 | ZNF598 | ZNF599 | ZNF600 | ZNF603P | ZNF605 | ZNF606 | ZNF607 | ZNF608 | ZNF609 | ZNF610 | ZNF611 | ZNF613 | ZNF614 | ZNF615 | ZNF616 | ZNF618 | ZNF619 | ZNF620 | ZNF621 | ZNF622 | ZNF623 | ZNF624 | ZNF625 | ZNF625-ZNF20 | ZNF626 | ZNF627 | ZNF628 | ZNF629 | ZNF630 | ZNF638 | ZNF639 | ZNF641 | ZNF644 | ZNF646 | ZNF648 | ZNF649 | ZNF652 | ZNF652-AS1 | ZNF653 | ZNF654 | ZNF655 | ZNF658 | ZNF658B | ZNF66 | ZNF660 | ZNF662 | ZNF663P | ZNF664 | ZNF664-RFLNA | ZNF665 | ZNF667 | ZNF667-AS1 | ZNF668 | ZNF669 | ZNF670 | ZNF670-ZNF695 | ZNF671 | ZNF672 | ZNF674 | ZNF674-AS1 | ZNF675 | ZNF676 | ZNF677 | ZNF678 | ZNF679 | ZNF680 | ZNF681 | ZNF682 | ZNF683 | ZNF684 | ZNF687 | ZNF688 | ZNF689 | ZNF69 | ZNF691 | ZNF692 | ZNF695