Target Name: ZNF438
NCBI ID: G220929
Other Name(s): Zinc finger protein 438, transcript variant 6 | Zinc finger protein 438, transcript variant 1 | Zinc finger protein 438 (isoform b) | BA330O11.1 | Zinc finger protein 438 (isoform a) | Zinc finger protein 438, transcript variant 5 | ZNF438 variant 6 | ZN438_HUMAN | bA330O11.1 | ZNF438 variant 1 | ZNF438 variant 7 | zinc finger protein 438 | Zinc finger protein 438 (isoform c) | ZNF438 variant 5 | RP11-330O11.1 | Zinc finger protein 438 | Zinc finger protein 438, transcript variant 7

ZNF438: A Potential Drug Target and Biomarker

Zinc finger proteins (ZFPs) are a family of non-coding RNAs that play a crucial role in various cellular processes. ZNF438, also known as Zinc finger protein 438, is a ZFP that is expressed in various tissues and is known to participate in various cellular processes, including cell growth, differentiation, and inflammation.

Expression and Localization

ZNF438 is a 21-kDa protein that is expressed in various tissues, including liver, lung, heart, kidney, and brain. It is predominantly expressed in the liver and has been shown to localize to the endoplasmic reticulum (ER) and the nuclear envelope (NE).

Function and Interaction

ZNF438 is a zinc finger protein that contains four zinc fingers and is characterized by a conserved catalytic core and a distinct N-terminus that is involved in protein-protein interactions and signaling. ZNF438 has been shown to play a role in various cellular processes, including cell growth, differentiation, and inflammation.

Drug Target Potential

ZNF438 has been identified as a potential drug target due to its unique structure and its involvement in various cellular processes. The zinc finger domain of ZNF438 has been shown to be involved in protein-protein interactions and can modulate the activity of various enzymes, including tyrosine kinases, mitochondrial fusion proteins, and G protein-coupled receptors.

In addition, ZNF438 has been shown to play a role in the regulation of cellular processes, including cell growth, apoptosis, and inflammation. ZNF438 has also been shown to be involved in the regulation of gene expression, including the regulation of stem cell proliferation and the establishment of tissue-specific gene expression patterns.

Biomarker Potential

ZNF438 has also been identified as a potential biomarker for various diseases, including cancer, neurodegenerative diseases, and autoimmune diseases. The expression of ZNF438 has been shown to be altered in various diseases, including cancer, neurodegenerative diseases, and autoimmune diseases.

Conclusion

In conclusion, ZNF438 is a unique protein that has been identified as a potential drug target and biomarker. Its unique structure and its involvement in various cellular processes make it an attractive target for drug development. Further research is needed to fully understand the role of ZNF438 in various cellular processes and its potential as a drug target and biomarker.

Protein Name: Zinc Finger Protein 438

Functions: Isoform 1 acts as a transcriptional repressor

More Common Targets

ZNF439 | ZNF44 | ZNF440 | ZNF441 | ZNF442 | ZNF443 | ZNF444 | ZNF445 | ZNF446 | ZNF449 | ZNF45 | ZNF451 | ZNF454 | ZNF460 | ZNF461 | ZNF462 | ZNF467 | ZNF468 | ZNF469 | ZNF470 | ZNF471 | ZNF473 | ZNF473CR | ZNF479 | ZNF48 | ZNF480 | ZNF483 | ZNF484 | ZNF485 | ZNF486 | ZNF487 | ZNF488 | ZNF490 | ZNF491 | ZNF492 | ZNF493 | ZNF496 | ZNF497 | ZNF497-AS1 | ZNF500 | ZNF501 | ZNF502 | ZNF503 | ZNF503-AS1 | ZNF503-AS2 | ZNF506 | ZNF507 | ZNF510 | ZNF511 | ZNF512 | ZNF512B | ZNF513 | ZNF514 | ZNF516 | ZNF516-DT | ZNF517 | ZNF518A | ZNF518B | ZNF519 | ZNF519P3 | ZNF521 | ZNF524 | ZNF525 | ZNF526 | ZNF527 | ZNF528 | ZNF528-AS1 | ZNF529 | ZNF529-AS1 | ZNF530 | ZNF532 | ZNF534 | ZNF536 | ZNF540 | ZNF541 | ZNF542P | ZNF543 | ZNF544 | ZNF546 | ZNF547 | ZNF548 | ZNF549 | ZNF550 | ZNF551 | ZNF552 | ZNF554 | ZNF555 | ZNF556 | ZNF557 | ZNF558 | ZNF559 | ZNF559-ZNF177 | ZNF560 | ZNF561 | ZNF561-AS1 | ZNF562 | ZNF563 | ZNF564 | ZNF565 | ZNF566