Target Name: ZNF426
NCBI ID: G79088
Other Name(s): Zinc finger protein 426 (isoform 1) | Zinc finger protein 426, transcript variant 1 | KSHV RTA binding protein | ZNF426 variant 1 | Zinc finger protein 426 | K-RBP | ZN426_HUMAN | CTC-543D15.7 | zinc finger protein 426

ZNF426: A Potential Drug Target and Biomarker

Zinc finger proteins (ZFPs) are a family of transmembrane proteins that play a crucial role in various cellular processes. ZNF426, also known as zinc finger protein 426 (isoform 1), is a ZFP that is expressed in various tissues and has been linked to various biological processes, including cell growth, differentiation, and disease.

Gene Structure and Function

The ZNF426 gene is located on chromosome 6p21 and encodes a 21-kDa protein that contains a zinc finger domain, as its name suggests. The zinc finger domain is a conserved region that is characterized by a specific arrangement of amino acids, which is thought to be involved in protein-protein interactions and other non-covalent interactions.

Expression and Localization

ZNF426 is expressed in various tissues, including brain, heart, liver, and pancreas, and has been shown to localize to the cytoplasm, endoplasmic reticulum, and nuclear envelope. It has also been shown to be involved in various cellular processes, including cell adhesion, migration, and invasion.

Disease associated with ZNF426

Several studies have identified ZNF426 as a potential drug target and biomarker for various diseases, including cancer, neurodegenerative diseases, and autoimmune diseases. ZNF426 has been shown to be involved in various cellular processes that are disrupted in these diseases, including cell adhesion, migration, and invasion.

In addition, ZNF426 has also been shown to be involved in diseases that are associated with inflammation, such as rheumatoid arthritis and multiple sclerosis. By targeting ZNF426, researchers may be able to develop new treatments for these diseases.

Drug Interactions with ZNF426

Several drugs have been shown to interact with ZNF426, including inhibitors of the PI3K/Akt signaling pathway, which is thought to be involved in the regulation of cellular processes that are associated with ZNF426. These drugs have been shown to reduce the levels of ZNF426 in various tissues and to inhibit its function.

Conclusion

In conclusion, ZNF426 is a protein that is expressed in various tissues and is involved in various cellular processes. Its function has been linked to various diseases, including cancer, neurodegenerative diseases, and autoimmune diseases. Several drugs have been shown to interact with ZNF426, including inhibitors of the PI3K/Akt signaling pathway. Further research is needed to fully understand the role of ZNF426 in disease and to develop new treatments for these diseases.

Protein Name: Zinc Finger Protein 426

Functions: May be involved in transcriptional regulation

More Common Targets

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