HOX-A2: A Key Regulator of Tissue and Organ Development (G3199)

Target Name: HOXA2

NCBI ID: G3199

HOX-A2: A Key Regulator of Tissue and Organ Development

The Homeobox protein Hox-A2 (HOXA2) is a key regulator of gene expression in many organisms, including humans. It is a member of the HOX gene family, which encodes a family of transmembrane proteins that play a central role in the development and maintenance of various tissues and organs. Hox-A2 is involved in the regulation of a wide range of physiological processes, including cell growth, differentiation, and response to environmental stimuli.

HOX-A2 is a 21-kDa protein that is expressed in many tissues and organs, including the brain, heart, and gastrointestinal tract. It is primarily localized to the cytoplasm and has been shown to play a role in regulating the expression of target genes. Hox-A2 has been shown to interact with several other proteins, including Dazl (Dazl kinase 1), which is a known co-factor of Hox-A2 and is involved in the regulation of stem cell maintenance.

HOX-A2 is a potential drug target and has been identified as a potential biomarker for several diseases, including cancer. Hox-A2 has been shown to be overexpressed in a variety of cancer types, including breast, ovarian, and prostate cancers. It is also overexpressed in diseases that are characterized by inflammation, such as rheumatoid arthritis and Crohn's disease.

HOX-A2 is involved in the regulation of a wide range of biological processes, including cell growth, differentiation, and response to environmental stimuli. It is a key regulator of the expression of target genes and has been shown to interact with several other proteins.

HOX-A2 is a 21-kDa protein that is expressed in many tissues and organs, including the brain, heart, and gastrointestinal tract. It is primarily localized to the cytoplasm and has been shown to play a role in regulating the expression of target genes.

HOX-A2 has been shown to interact with several other proteins, including Dazl, which is a known co-factor of Hox-A2 and is involved in the regulation of stem cell maintenance.

HOX-A2 is a potential drug target and has been identified as a potential biomarker for several diseases, including cancer. It is overexpressed in a variety of cancer types, including breast, ovarian, and prostate cancers. It is also overexpressed in diseases that are characterized by inflammation, such as rheumatoid arthritis and Crohn's disease.

Conclusion

HOX-A2 is a key regulator of gene expression that is involved in the regulation of a wide range of physiological processes. It is a potential drug target and has been identified as a potential biomarker for several diseases, including cancer. Further research is needed to fully understand the role of Hox-A2 in biology and to develop effective treatments for diseases associated with its dysfunction.

Protein Name: Homeobox A2

Functions: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis

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