Understanding OR4M2: Potential Drug Targets and Biomarkers (G390538)

Understanding OR4M2: Potential Drug Targets and Biomarkers

OR4M2 (OR4M2_HUMAN), a protein encoded in the human gene OR4M2, is a potential drug target and biomarker associated with various diseases, including cancer, neurodegenerative disorders, and cardiovascular diseases. OR4M2 is a member of the OR4M2 gene family, which is known to encode a protein involved in the regulation of mitochondrial fusion and fusion-related processes.

The OR4M2 gene has four splice variants, OR4M2-long, OR4M2-middle, OR4M2-short, and OR4M2-long reverse. OR4M2-long is the most abundant splice variant, accounting for approximately 95% of the total OR4M2 gene expression in human cells. OR4M2-middle and OR4M2-short are less abundant, representing only about 5% and 1% of the total OR4M2 gene expression, respectively.

OR4M2 is a 21-kDa protein that is expressed in various tissues and cells of the human body. It is primarily localized to the mitochondria, where it plays a role in regulating mitochondrial fusion and fusion-related processes. OR4M2 is involved in the formation of mitochondrial stress-gray channels, which are critical for the regulation of mitochondrial fusion and the maintenance of cellular homeostasis.

OR4M2 has been implicated in various diseases, including cancer, neurodegenerative disorders, and cardiovascular diseases. In cancer, OR4M2 has been shown to be involved in the regulation of mitochondrial function, which can contribute to the development and progression of cancer. For example, OR4M2 has been shown to play a role in the regulation of mitochondrial DNA replication, which is critical for the maintenance of genetic stability in cancer cells.

In neurodegenerative disorders, OR4M2 has been implicated in the regulation of mitochondrial function and has been shown to be involved in the development and progression of various neurodegenerative disorders. For example, OR4M2 has been shown to play a role in the regulation of mitochondrial neurotransmitter synthesis and release, which is critical for the maintenance of cellular homeostasis and the development of neurotransmitter-mediated signaling systems.

In cardiovascular diseases, OR4M2 has been shown to be involved in the regulation of mitochondrial function and has been implicated in the development and progression of various cardiovascular diseases. For example, OR4M2 has been shown to play a role in the regulation of mitochondrial inflammation, which is critical for the development and progression of cardiovascular diseases.

Despite the potential involvement of OR4M2 in various diseases, little is known about its specific functions and the underlying mechanisms that regulate its activity. Therefore, further research is needed to fully understand the role of OR4M2 in diseases and to identify potential drug targets and biomarkers associated with OR4M2.

In conclusion, OR4M2 is a protein that has been implicated in various diseases, including cancer, neurodegenerative disorders, and cardiovascular diseases. Its functions and the underlying mechanisms that regulate its activity are not well understood. Further research is needed to fully understand the role of OR4M2 in diseases and to identify potential drug targets and biomarkers associated with OR4M2.

Protein Name: Olfactory Receptor Family 4 Subfamily M Member 2

Functions: Odorant receptor

More Common Targets

OR4M2-OT1 | OR4N2 | OR4N3P | OR4N4 | OR4N5 | OR4P4 | OR4Q3 | OR4S1 | OR4S2 | OR4T1P | OR4V1P | OR4X1 | OR4X2 | OR51A1P | OR51A2 | OR51A3P | OR51A4 | OR51A6P | OR51A7 | OR51B2 | OR51B4 | OR51B5 | OR51B6 | OR51C1P | OR51D1 | OR51E1 | OR51E2 | OR51F1 | OR51F2 | OR51G1 | OR51G2 | OR51H1 | OR51I1 | OR51I2 | OR51J1 | OR51L1 | OR51M1 | OR51Q1 | OR51S1 | OR51T1 | OR51V1 | OR52A1 | OR52A4P | OR52A5 | OR52B2 | OR52B4 | OR52B6 | OR52D1 | OR52E1 | OR52E2 | OR52E4 | OR52E5 | OR52E6 | OR52E8 | OR52H1 | OR52I1 | OR52I2 | OR52J3 | OR52K1 | OR52K2 | OR52K3P | OR52L1 | OR52M1 | OR52N1 | OR52N4 | OR52N5 | OR52R1 | OR52W1 | OR52Z1P | OR56A1 | OR56A3 | OR56A4 | OR56A5 | OR56B1 | OR56B4 | OR5A1 | OR5A2 | OR5AC1 | OR5AC2 | OR5AK2 | OR5AK4P | OR5AN1 | OR5AP2 | OR5AR1 | OR5AS1 | OR5AU1 | OR5B12 | OR5B17 | OR5B2 | OR5B21 | OR5B3 | OR5BA1P | OR5C1 | OR5D13 | OR5D14 | OR5D16 | OR5D17P | OR5D18 | OR5E1P | OR5F1