Target Name: OR51E1
NCBI ID: G143503
Other Name(s): olfactory receptor, family 51, subfamily E, member 1 pseudogene | prostate-specific G protein-coupled receptor 2 | GPR164 | olfactory receptor 52A3 | GPR136 | D-GPCR | POGR | Prostate overexpressed G protein-coupled receptor | olfactory receptor, family 52, subfamily A, member 3 pseudogene | OR52A3P | olfactory receptor OR11-15 | DGPCR | Olfactory receptor, family 51, subfamily E, member 1 | O51E1_HUMAN | Olfactory receptor 51E1 | Prostate-specific G protein-coupled receptor 2 | MGC24137 | OR51E1P | PSGR2 | Prostate-overexpressed G protein-coupled receptor | Dresden-G-protein-coupled receptor | G-protein coupled receptor 164 | Olfactory receptor OR11-15 | Olfactory receptor family 51 subfamily E member 1 | olfactory receptor family 51 subfamily E member 1 | Olfactory receptor 52A3 | prostate overexpressed G protein-coupled receptor

OR51E1: A Pseudogene Encoding Olfactory Receptor Protein

OR51E1 (Olfactory Receptor, Family 51, Subfamily E, Member 1 Pseudogene) is a gene that encodes for a protein known as OR51E1. OR51E1 is a member of the Olfactory Receptor family, which is responsible for transmitting sensory information from the nose and mouth to the brain. The OR51E1 gene has been identified as a potential drug target and biomarker for several diseases, including cancer, neurodegenerative diseases, and psychiatric disorders.

The OR51E1 gene is located on chromosome 11p and has a length of approximately 3,450 base pairs. OR51E1 is a pseudogene, which means that it is a non-functional copy of a gene that has been deleted or mutated. Despite its non-functional nature, OR51E1 is still a promising candidate for drug targeting due to its unique structure and location on the genome.

One of the key features of OR51E1 is its high conservation across different species. OR51E1 has a similar sequence to other Olfactory Receptor genes, including those from humans, mice, and dogs. This conservation suggests that OR51E1 may be a useful target for drugs that are effective against Olfactory Receptor-mediated signaling pathways.

In addition to its conserved sequence, OR51E1 has also been shown to be involved in several disease processes. For example, OR51E1 has been linked to several neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease, and Huntington's disease. These conditions are characterized by the progressive loss of brain cells and the development of severe cognitive impairments.

OR51E1 has also been shown to be involved in cancer, specifically, in the development of olfactory nerve tumors. Olfactory nerve tumors are rare tumors that originate from the olfactory neuroepithelium. Studies have found that variations and mutations in the OR51E1 gene may lead to the occurrence of olfactory nerve tumors.

Beyond that, OR51E1 has been linked to mental health. There is evidence that variations and mutations in the OR51E1 gene are associated with mental health problems such as depression, anxiety, and attention deficit hyperactivity disorder (ADHD).

Therefore, OR51E1 is a promising drug target or biomarker, attracting the interest of many scientists and drug companies. In the future, research will continue to delve into the role of OR51E1 in drug discovery and treatment to better understand its pathogenesis and develop new drugs.

Protein Name: Olfactory Receptor Family 51 Subfamily E Member 1

Functions: Odorant receptor

More Common Targets

OR51E2 | OR51F1 | OR51F2 | OR51G1 | OR51G2 | OR51H1 | OR51I1 | OR51I2 | OR51J1 | OR51L1 | OR51M1 | OR51Q1 | OR51S1 | OR51T1 | OR51V1 | OR52A1 | OR52A4P | OR52A5 | OR52B2 | OR52B4 | OR52B6 | OR52D1 | OR52E1 | OR52E2 | OR52E4 | OR52E5 | OR52E6 | OR52E8 | OR52H1 | OR52I1 | OR52I2 | OR52J3 | OR52K1 | OR52K2 | OR52K3P | OR52L1 | OR52M1 | OR52N1 | OR52N4 | OR52N5 | OR52R1 | OR52W1 | OR52Z1P | OR56A1 | OR56A3 | OR56A4 | OR56A5 | OR56B1 | OR56B4 | OR5A1 | OR5A2 | OR5AC1 | OR5AC2 | OR5AK2 | OR5AK4P | OR5AN1 | OR5AP2 | OR5AR1 | OR5AS1 | OR5AU1 | OR5B12 | OR5B17 | OR5B2 | OR5B21 | OR5B3 | OR5BA1P | OR5C1 | OR5D13 | OR5D14 | OR5D16 | OR5D17P | OR5D18 | OR5E1P | OR5F1 | OR5H1 | OR5H14 | OR5H15 | OR5H2 | OR5H4P | OR5H6 | OR5I1 | OR5K1 | OR5K2 | OR5K3 | OR5K4 | OR5L1 | OR5L2 | OR5M1 | OR5M10 | OR5M11 | OR5M3 | OR5M4P | OR5M8 | OR5M9 | OR5P1P | OR5P2 | OR5P3 | OR5T1 | OR5T2 | OR5T3