Understanding The Role of RPLP0P12 in Disease (G390860)

Target Name: RPLP0P12

NCBI ID: G390860

Other Name(s): Ribosomal protein, large, P0 pseudogene | ribosomal protein lateral stalk subunit P0 pseudogene 12 | LOC390860

Understanding The Role of RPLP0P12 in Disease

Ribosomal protein, large (RPLP0P12), is a protein that plays a critical role in the process of translation of mRNA into proteins. Mutations in the RPLP0P12 gene have been linked to a variety of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. As a result, RPLP0P12 has become a focus of interest for researchers as a potential drug target or biomarker.

The RPLP0P12 gene is located on chromosome 12q and encodes a protein of 18.8 kDa. The protein is composed of 166 amino acids and has a calculated pI of 6.5. RPLP0P12 is expressed in most tissues and cells and is primarily localized to the endoplasmic reticulum (ER) and the cytoplasm.

Mutations in the RPLP0P12 gene have been linked to a variety of diseases. For example, a missense mutation has been linked to the development of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease. In addition, RPLP0P12 mutations have also been linked to the development of cancer, including breast and ovarian cancers.

The functional role of RPLP0P12 in the process of translation is not well understood, but it is known to play a key role in the formation of the endoplasmic reticulum. RPLP0P12 is one of the proteins that help to transport proteins from the cytoplasm to the ER and is thought to play a key role in the process of protein folding.

As a result of its involvement in the translation process and its potential role in the development of disease, RPLP0P12 has become a focus of interest for researchers as a potential drug target or biomarker. Researchers are currently working to develop small molecules that can inhibit the activity of RPLP0P12 and use this information to develop new treatments for a variety of diseases.

In addition to its potential as a drug target or biomarker, RPLP0P12 also has potential as a research tool. Researchers can use the RPLP0P12 gene to study the effects of different genetic and environmental factors on protein synthesis and to gain insights into the underlying mechanisms of its involvement in disease.

Overall, RPLP0P12 is a protein that has important roles in the process of translation and has been linked to a variety of diseases. As a result, it is a focus of interest for researchers as a potential drug target or biomarker. Further research is needed to fully understand its functional role in the cell and to develop effective treatments for a variety of diseases.

Protein Name: Ribosomal Protein Lateral Stalk Subunit P0 Pseudogene 12

More Common Targets