PRAMEF8: A Potential Drug Target Or Biomarker (G391002)

Target Name: PRAMEF8

NCBI ID: G391002

Other Name(s): PRAM8_HUMAN | PRAMEF24 | PRAME family member 8 | putative PRAME family member 24

PRAMEF8: A Potential Drug Target Or Biomarker

PRAMEF8 (PRAM8_HUMAN), a protein that is expressed in various tissues of the human body, including the brain, heart, and blood vessels, has been identified as a potential drug target or biomarker in various medical conditions. Its function and significance have been studied extensive in the scientific literature, and its potential as a therapeutic target is under investigation.

PRAMEF8 is a member of the PRAM8 family, which includes several related proteins that are involved in various cellular processes, including cell signaling, DNA replication, and chromatin remodeling. These proteins have been implicated in the development and progression of various diseases, including cancer, neurodegenerative diseases, and cardiovascular diseases.

One of the key functions of PRAMEF8 is its role in cell signaling. It is a potent negative regulator of the protein kinase A3 (AP-1), which is involved in cell growth, differentiation, and survival. PRAMEF8 has been shown to inhibit the activity of AP-1 and to play a role in the regulation of cell proliferation and survival.

PRAMEF8 has also been shown to be involved in the regulation of DNA replication. It is a critical component of the DNA replication machinery, and is required for the efficient replication of DNA in the human body. PRAMEF8 has been shown to play a role in the regulation of DNA replication in various cell types, including cancer cells.

In addition to its role in cell signaling and DNA replication, PRAMEF8 has also been shown to be involved in the regulation of chromatin remodeling. It is a regulator of the chromatin remodeling complex, which is involved in the modification and organization of chromatin in the nucleus of the cell. PRAMEF8 has been shown to play a role in the regulation of chromatin remodeling in various cell types, including cancer cells.

The therapeutic potential uses of PRAMEF8 are vast, and its potential as a drug target or biomarker are being investigated in various medical conditions. For example, PRAMEF8 has been shown to be involved in the regulation of cell proliferation and survival, making it a potential target for anti-cancer drugs. In addition, its role in cell signaling and DNA replication make it a potential target for neurodegenerative diseases and cardiovascular diseases.

PRAMEF8 is also a good candidate as a biomarker for various diseases. Its expression is known to be altered in various diseases, including cancer, neurodegenerative diseases, and cardiovascular diseases. This makes it a potential indicator of disease status and a target for diagnostic tests.

In conclusion, PRAMEF8 is a protein that has been identified as a potential drug target or biomarker in various medical conditions. Its functions and significance have been studied extensively in the scientific literature, and its potential as a therapeutic target or biomarker is under investigation. Further research is needed to fully understand its role in the regulation of cellular processes and its potential as a therapeutic target or biomarker.

Protein Name: PRAME Family Member 8

More Common Targets