PRDM8: A Potential Drug Target for Cancer Treatment (G56978)

Target Name: PRDM8

NCBI ID: G56978

PRDM8: A Potential Drug Target for Cancer Treatment

PRDM8 (PR disease domain 8) is a gene that has been identified as a potential drug target or biomarker for the treatment of various diseases, including cancer. The gene is located on chromosome 6 and encodes a protein known as PRDM8.

PRDM8 is a key regulator of cell division and has been shown to play a role in the development and progression of various diseases, including cancer. The protein encoded by PRDM8 has been shown to promote the growth and division of cancer cells, and it is also involved in the regulation of cell death.

One of the key features of PRDM8 is its ability to interact with other genes and proteins. This interaction has been shown to play a role in the development and progression of various diseases, including cancer. For example, studies have shown that PRDM8 can interact with the protein PDGFR, which is involved in the development of many types of cancer.

Another key feature of PRDM8 is its ability to regulate the expression of other genes. This regulation has been shown to play a role in the development and progression of various diseases, including cancer. For example, studies have shown that PRDM8 can interact with the gene NF-kappa-B, which is involved in the regulation of inflammation and immune responses.

In addition to its role in the development and progression of diseases, PRDM8 is also a potential drug target. Studies have shown that PRDM8 can be targeted by small molecules, such as inhibitors, which can inhibit its interaction with other genes and proteins. This targeting has the potential to lead to the development of new treatments for various diseases, including cancer.

Overall, PRDM8 is a gene that has the potential to be a drug target or biomarker for the treatment of various diseases, including cancer. Further research is needed to fully understand its role and to develop effective treatments.

Protein Name: PR/SET Domain 8

Functions: Probable histone methyltransferase, preferentially acting on 'Lys-9' of histone H3 (By similarity). Involved in the control of steroidogenesis through transcriptional repression of steroidogenesis marker genes such as CYP17A1 and LHCGR (By similarity). Forms with BHLHE22 a transcriptional repressor complex controlling genes involved in neural development and neuronal differentiation (By similarity). In the retina, it is required for rod bipolar and type 2 OFF-cone bipolar cell survival (By similarity)

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