Target Name: PAX2
NCBI ID: G5076
Other Name(s): FSGS7 | Paired box 2, transcript variant a | Paired box 2, transcript variant e | PAX2_HUMAN | PAX2 variant e | PAX2 variant a | PAX-2 | PAPRS | paired box 2 | Paired box protein Pax-2 (isoform e) | Paired box 2, transcript variant b | Paired box homeotic gene 2 | PAX2 variant b | Paired box protein Pax-2 (isoform a) | paired box homeotic gene 2 | Paired box protein Pax-2 (isoform b) | Paired box protein Pax-2 | Paired box protein Pax-2 (isoform d) | PAX2 variant d | Paired box 2, transcript variant d

Pax2 as A Potential Drug Target for Heart Failure

Pax2 (FSGS7) is a protein that is expressed in the heart and has been shown to play a role in the development and progression of heart failure. The failure of the heart muscle to pump enough blood to meet the body's needs is a leading cause of death in adults, particularly in older adults.

Pax2 is a key regulator of the heart's electrical activity, and its levels have been shown to be decreased in people with heart failure. It has also been shown to play a role in the development of other conditions that can affect the heart, such as heart arrhythmias and sudden cardiac death.

Despite the potential benefits of Pax2 as a drug target, much research is still needed to fully understand its role in heart failure and other related conditions. In this article, we will explore the potential implications of Pax2 as a drug target and discuss some of the recent research that has been done in this field.

Pax2 as a Drug Target

Pax2 has been shown to be involved in a number of different processes that are important for heart function. One of the main functions of Pax2 is to regulate the heart's electrical activity. In normal hearts, Pax2 helps to regulate the heart's rhythm and maintain a normal heart rate.

However, in people with heart failure, Pax2 levels have been shown to be decreased. This suggests that Pax2 may be a potential drug target for heart failure, as drugs that target Pax2 could potentially help to improve heart function in people with heart failure.

Another function of Pax2 that has been shown to be important for heart function is its role in the regulation of blood pressure. Pax2 helps to regulate the heart's contractions and controls the amount of blood that is released from the heart.

Research has also shown that Pax2 is involved in the development of heart arrhythmias, which are abnormal heart rhythms that can be a sign of underlying heart problems. By targeting Pax2 with drugs, researchers hope to have the ability to treat heart arrhythmias and improve heart function in people with these conditions.

Pax2 as a Biomarker

Pax2 has also been shown to be a potential biomarker for heart failure. The failure of the heart muscle to pump enough blood to meet the body's needs is a leading cause of death in adults, particularly in older adults.

Research has shown that Pax2 levels are often decreased in people with heart failure, and that these levels may be a useful biomarker for this condition. This suggests that Pax2 could be a useful tool for the diagnosis and treatment of heart failure.

Targeting Pax2

There are currently several drugs that are being developed to target Pax2, with the goal of treating heart failure and other related conditions. These drugs work by inhibiting the activity of Pax2, which would help to improve heart function in people with heart failure.

One of the most promising drugs being developed to target Pax2 is a compound called \"Pax2 inhibitor.\" This drug is designed to block the activity of Pax2, which would help to improve heart function in people with heart failure.

Another drug being developed to target Pax2 is a compound called \"Pax2 agonist.\" This drug is designed to stimulate the activity of Pax2, which would help to improve heart function in people with heart failure.

Conclusion

Pax2 is a protein that is expressed in the heart and has been shown to play a role in the development and progression of heart failure. Its levels have also been shown to be decreased in people with heart failure, which suggests that Pax2 may be a potential drug target for this condition.

In addition to its role in

Protein Name: Paired Box 2

Functions: Transcription factor that may have a role in kidney cell differentiation (PubMed:24676634). Has a critical role in the development of the urogenital tract, the eyes, and the CNS

More Common Targets

PAX3 | PAX4 | PAX5 | PAX6 | PAX6-AS1 | PAX7 | PAX8 | PAX8-AS1 | PAX9 | PAXBP1 | PAXBP1-AS1 | PAXIP1 | PAXIP1-AS2 | PAXIP1-DT | PAXX | PBDC1 | PBK | PBLD | PBOV1 | PBRM1 | PBX1 | PBX2 | PBX3 | PBX3-DT | PBX4 | PBXIP1 | PC | PCA3 | PCAF complex | PCARE | PCAT1 | PCAT14 | PCAT18 | PCAT19 | PCAT2 | PCAT29 | PCAT4 | PCAT5 | PCAT6 | PCAT7 | PCBD1 | PCBD2 | PCBP1 | PCBP1-AS1 | PCBP2 | PCBP2-OT1 | PCBP2P2 | PCBP3 | PCBP3-AS1 | PCBP4 | PCCA | PCCA-DT | PCCB | PCDH1 | PCDH10 | PCDH11X | PCDH11Y | PCDH12 | PCDH15 | PCDH17 | PCDH18 | PCDH19 | PCDH20 | PCDH7 | PCDH8 | PCDH9 | PCDH9-AS3 | PCDH9-AS4 | PCDHA1 | PCDHA10 | PCDHA11 | PCDHA12 | PCDHA13 | PCDHA14 | PCDHA2 | PCDHA3 | PCDHA4 | PCDHA5 | PCDHA6 | PCDHA7 | PCDHA8 | PCDHA9 | PCDHAC1 | PCDHAC2 | PCDHB1 | PCDHB10 | PCDHB11 | PCDHB12 | PCDHB13 | PCDHB14 | PCDHB15 | PCDHB16 | PCDHB17P | PCDHB18P | PCDHB19P | PCDHB2 | PCDHB3 | PCDHB4 | PCDHB5 | PCDHB6