Target Name: NMD3
NCBI ID: G51068
Other Name(s): 60S ribosomal export protein NMD3 | NMD3 variant 2 | NMD3 homolog | CGI-07 | hNMD3 | NMD3_HUMAN | NMD3 ribosome export adaptor, transcript variant 2 | NMD3 ribosome export adaptor | 60S ribosomal export protein NMD3 (isoform 2)

NMD3: A Potential Drug Target and Biomarker

NMD3 (60S ribosomal export protein NMD3) is a protein that is expressed in various cell types, including muscle and cardiac cells, and plays a critical role in the regulation of gene expression. NMD3 has been identified as a potential drug target and biomarker due to its unique structure and function.

The 60S ribosomal export protein NMD3 is a protein that is composed of 156 amino acid residues and has a calculated molecular weight of 18.5 kDa. It is expressed in various cell types, including muscle and cardiac cells, and is involved in the regulation of gene expression by binding to specific DNA sequences.

One of the unique features of NMD3 is its ability to interact with specific DNA sequences. NMD3 has been shown to bind to the protein responsible for the transcription factor YAP/TAZ, which is a critical regulator of cell growth and differentiation. This interaction between NMD3 and YAP/TAZ has been shown to play a role in the regulation of various cellular processes, including cell growth, migration, and invasion.

Another potential drug target for NMD3 is its role in the regulation of cell apoptosis. NMD3 has been shown to play a role in the regulation of cell apoptosis, which is a natural process that helps maintain the homeostasis of cells. NMD3 has been shown to interact with the protein Bcl-2, which is a protein that is involved in the regulation of cell apoptosis. This interaction between NMD3 and Bcl-2 has been shown to play a role in the regulation of cell apoptosis and may be a potential drug target for NMD3.

In addition to its potential drug target properties, NMD3 has also been identified as a potential biomarker. The regulation of gene expression by NMD3 is known to play a role in the development and progression of various diseases, including cancer. NMD3 has been shown to be expressed in various types of cancer, including breast, ovarian, and colorectal cancer. This suggests that NMD3 may be a useful biomarker for the diagnosis and treatment of these diseases.

In conclusion, NMD3 is a protein that has unique structure and function, and its potential as a drug target and biomarker makes it an attractive target for further research. Further studies are needed to fully understand the regulation of gene expression by NMD3 and its potential as a drug target and biomarker.

Protein Name: NMD3 Ribosome Export Adaptor

Functions: Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit

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