BFAR: A Potential Drug Target for Neurodegenerative Diseases (G51283)
BFAR: A Potential Drug Target for Neurodegenerative Diseases
BFAR (Brain-FGF-Activated Receptor) is a protein that is expressed in the nervous system and has been identified as a potential drug target in the field of neurodegenerative diseases. The full name of the receptor is BFAR-related neurotrophic factor (BFAR), and it is a member of the TGF-β receptor superfamily. This protein is involved in the development and progression of various neurological disorders, including Alzheimer's disease, Parkinson's disease, and other neurodegenerative diseases.
The BFAR protein is composed of 115 amino acid residues and has a calculated molecular weight of 13.9 kDa. It is expressed in the central nervous system (CNS) and is involved in the development and progression of neurodegenerative diseases. The BFAR protein is a potent negative regulator of the TGF-β pathway, which is a well-established pathway involved in the development and progression of neurodegenerative diseases.
The TGF-β pathway is a complex intracellular signaling pathway that is involved in the development and progression of neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease, and other neurodegenerative diseases. The TGF-β pathway is a transcription factor that regulates the expression of genes involved in the development and progression of neurodegenerative diseases. The BFAR protein is involved in the regulation of the TGF-β pathway by inhibiting the activity of the TGF-β receptor.
The BFAR protein is involved in the development and progression of neurodegenerative diseases by regulating the TGF-β pathway. The TGF-β pathway is involved in the development and progression of neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease, and other neurodegenerative diseases. The BFAR protein is a potent negative regulator of the TGF-β pathway, which means that it inhibits the activity of the TGF-β receptor and protects against the development and progression of neurodegenerative diseases.
The BFAR protein is also involved in the regulation of cell survival and proliferation. It is a negative regulator of the TGF-β pathway, which means that it inhibits the activity of the TGF-β receptor and protects against the development and progression of neurodegenerative diseases. The BFAR protein helps to maintain the stability of the nervous system by regulating the number of neurons that are produced and the duration of their life.
The BFAR protein is also involved in the regulation of neurotransmitter release. It is a negative regulator of the TGF-β pathway, which means that it inhibits the activity of the TGF-β receptor and protects against the development and progression of neurodegenerative diseases. The BFAR protein helps to regulate the release of neurotransmitters, such as dopamine and nitric oxide, which are involved in the transmission of signals in the nervous system.
The BFAR protein is also involved in the regulation of inflammation. It is a negative regulator of the TGF-β pathway, which means that it inhibits the activity of the TGF-β receptor and protects against the development and progression of neurodegenerative diseases. The BFAR protein helps to regulate the production of pro-inflammatory cytokines, which are involved in the development of neurodegenerative diseases.
The BFAR protein is also involved in the regulation of cell migration. It is a negative regulator of the TGF-β pathway, which means that it inhibits the activity of the TGF-β receptor and protects against the development and progression of neurodegenerative diseases. The BFAR protein helps to maintain the stability of the nervous system by regulating the movement of neurons and glial cells.
In conclusion, the BFAR protein is a potential drug target for the development of neurodegenerative diseases. The BFAR protein is involved in the development and progression of neurodegenerative diseases by regulating the TGF-β pathway. The BFAR protein is a potent negative regulator of the TGF-β pathway and is involved in the regulation of cell survival and proliferation, neurotransmission, inflammation, and cell migration. These properties make the BFAR protein an attractive target
Protein Name: Bifunctional Apoptosis Regulator
Functions: Apoptosis regulator. Has anti-apoptotic activity, both for apoptosis triggered via death-receptors and via mitochondrial factors
More Common Targets
BFSP1 | BFSP2 | BFSP2-AS1 | BGLAP | BGLT3 | BGN | BHC complex | BHLHA15 | BHLHA9 | BHLHE22 | BHLHE22-AS1 | BHLHE23 | BHLHE40 | BHLHE40-AS1 | BHLHE41 | BHMT | BHMT2 | BICC1 | BICD1 | BICD2 | BICDL1 | BICDL2 | BICRA | BICRAL | BID | BIK | BIN1 | BIN2 | BIN3 | BIN3-IT1 | Biogenesis of lysosome-related organelles complex-1 | BIRC2 | BIRC3 | BIRC5 | BIRC6 | BIRC7 | BIRC8 | BISPR | BIVM | BIVM-ERCC5 | BLACAT1 | BLACE | BLCAP | BLID | BLK | BLM | BLMH | BLNK | BLOC-1 (biogenesis of lysosome-related organelles complex 1) | BLOC1S1 | BLOC1S1-RDH5 | BLOC1S2 | BLOC1S3 | BLOC1S4 | BLOC1S5 | BLOC1S5-TXNDC5 | BLOC1S6 | BLTP1 | BLTP2 | BLTP3A | BLTP3B | BLVRA | BLVRB | BLZF1 | BMAL1 | BMAL2 | BMAL2-AS1 | BMERB1 | BMF | BMI1 | BMP1 | BMP10 | BMP15 | BMP2 | BMP2K | BMP3 | BMP4 | BMP5 | BMP6 | BMP7 | BMP8A | BMP8B | BMPER | BMPR1A | BMPR1B | BMPR1B-DT | BMPR2 | BMS1 | BMS1P1 | BMS1P10 | BMS1P14 | BMS1P15 | BMS1P17 | BMS1P18 | BMS1P2 | BMS1P20 | BMS1P21 | BMS1P22 | BMS1P4 | BMS1P7